Soil-type influences human selenium status and underlies widespread selenium deficiency risks in Malawi

Selenium (Se) is an essential human micronutrient with critical roles in immune functioning and antioxidant defence. Estimates of dietary Se intakes and status are scarce for Africa although crop surveys indicate deficiency is probably widespread in Malawi. Here we show that Se deficiency is likely...

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Main Authors: Hurst, Rachel, Siyame, Edwin W.P., Young, Scott D., Chilimba, Allan D.C., Joy, Edward J.M., Black, Colin R., Ander, E. Louise, Watts, Michael J., Chilima, Benson, Gondwe, Jellita, Kang’ombe, Dalitso, Stein, Alexander J., Fairweather-Tait, Susan J., Gibson, Rosalind S., Kalimbira, Alexander A., Broadley, Martin R.
Format: Article
Published: Nature Publishing Group 2013
Online Access:https://eprints.nottingham.ac.uk/2782/
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author Hurst, Rachel
Siyame, Edwin W.P.
Young, Scott D.
Chilimba, Allan D.C.
Joy, Edward J.M.
Black, Colin R.
Ander, E. Louise
Watts, Michael J.
Chilima, Benson
Gondwe, Jellita
Kang’ombe, Dalitso
Stein, Alexander J.
Fairweather-Tait, Susan J.
Gibson, Rosalind S.
Kalimbira, Alexander A.
Broadley, Martin R.
author_facet Hurst, Rachel
Siyame, Edwin W.P.
Young, Scott D.
Chilimba, Allan D.C.
Joy, Edward J.M.
Black, Colin R.
Ander, E. Louise
Watts, Michael J.
Chilima, Benson
Gondwe, Jellita
Kang’ombe, Dalitso
Stein, Alexander J.
Fairweather-Tait, Susan J.
Gibson, Rosalind S.
Kalimbira, Alexander A.
Broadley, Martin R.
author_sort Hurst, Rachel
building Nottingham Research Data Repository
collection Online Access
description Selenium (Se) is an essential human micronutrient with critical roles in immune functioning and antioxidant defence. Estimates of dietary Se intakes and status are scarce for Africa although crop surveys indicate deficiency is probably widespread in Malawi. Here we show that Se deficiency is likely endemic in Malawi based on the Se status of adults consuming food from contrasting soil types. These data are consistent with food balance sheets and composition tables revealing that >80% of the Malawi population is at risk of dietary Se inadequacy. Risk of dietary Se inadequacy is >60% in seven other countries in Southern Africa, and 22% across Africa as a whole. Given that most Malawi soils cannot supply sufficient Se to crops for adequate human nutrition, the cost and benefits of interventions to alleviate Se deficiency should be determined; for example, Se-enriched nitrogen fertilisers could be adopted as in Finland.
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spelling nottingham-27822020-05-04T16:36:03Z https://eprints.nottingham.ac.uk/2782/ Soil-type influences human selenium status and underlies widespread selenium deficiency risks in Malawi Hurst, Rachel Siyame, Edwin W.P. Young, Scott D. Chilimba, Allan D.C. Joy, Edward J.M. Black, Colin R. Ander, E. Louise Watts, Michael J. Chilima, Benson Gondwe, Jellita Kang’ombe, Dalitso Stein, Alexander J. Fairweather-Tait, Susan J. Gibson, Rosalind S. Kalimbira, Alexander A. Broadley, Martin R. Selenium (Se) is an essential human micronutrient with critical roles in immune functioning and antioxidant defence. Estimates of dietary Se intakes and status are scarce for Africa although crop surveys indicate deficiency is probably widespread in Malawi. Here we show that Se deficiency is likely endemic in Malawi based on the Se status of adults consuming food from contrasting soil types. These data are consistent with food balance sheets and composition tables revealing that >80% of the Malawi population is at risk of dietary Se inadequacy. Risk of dietary Se inadequacy is >60% in seven other countries in Southern Africa, and 22% across Africa as a whole. Given that most Malawi soils cannot supply sufficient Se to crops for adequate human nutrition, the cost and benefits of interventions to alleviate Se deficiency should be determined; for example, Se-enriched nitrogen fertilisers could be adopted as in Finland. Nature Publishing Group 2013-03-12 Article PeerReviewed Hurst, Rachel, Siyame, Edwin W.P., Young, Scott D., Chilimba, Allan D.C., Joy, Edward J.M., Black, Colin R., Ander, E. Louise, Watts, Michael J., Chilima, Benson, Gondwe, Jellita, Kang’ombe, Dalitso, Stein, Alexander J., Fairweather-Tait, Susan J., Gibson, Rosalind S., Kalimbira, Alexander A. and Broadley, Martin R. (2013) Soil-type influences human selenium status and underlies widespread selenium deficiency risks in Malawi. Scientific Reports, 3 (1425). ISSN 2045-2322 http://www.nature.com/srep/2013/130312/srep01425/full/srep01425.html doi:10.1038/srep01425 doi:10.1038/srep01425
spellingShingle Hurst, Rachel
Siyame, Edwin W.P.
Young, Scott D.
Chilimba, Allan D.C.
Joy, Edward J.M.
Black, Colin R.
Ander, E. Louise
Watts, Michael J.
Chilima, Benson
Gondwe, Jellita
Kang’ombe, Dalitso
Stein, Alexander J.
Fairweather-Tait, Susan J.
Gibson, Rosalind S.
Kalimbira, Alexander A.
Broadley, Martin R.
Soil-type influences human selenium status and underlies widespread selenium deficiency risks in Malawi
title Soil-type influences human selenium status and underlies widespread selenium deficiency risks in Malawi
title_full Soil-type influences human selenium status and underlies widespread selenium deficiency risks in Malawi
title_fullStr Soil-type influences human selenium status and underlies widespread selenium deficiency risks in Malawi
title_full_unstemmed Soil-type influences human selenium status and underlies widespread selenium deficiency risks in Malawi
title_short Soil-type influences human selenium status and underlies widespread selenium deficiency risks in Malawi
title_sort soil-type influences human selenium status and underlies widespread selenium deficiency risks in malawi
url https://eprints.nottingham.ac.uk/2782/
https://eprints.nottingham.ac.uk/2782/
https://eprints.nottingham.ac.uk/2782/