Molecular mechanisms of enhanced expression of the chemokine interleukin 8 (CXCL8) in cystic fibrosis (CF) airway epithelial cells

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Molecular mechanisms of enhanced expression of the chemokine interleukin 8 (CXCL8) in cystic fibrosis (CF) airway epithelial cells

Cystic fibrosis (CF) is a fatal disease caused by a mutation of the CFTR gene and severe inflammation of the lungs. The inflammatory process is characterised by increased production of the potent neutrophil-attracting chemokine interleukin 8 (CXCL8), but the mechanism responsible is poorly understoo...

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Bibliographic Details
Main Author:	Poghosyan, Anna
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2014
Subjects:	Cystic fibrosis Interleukin-8 Epigenetic regulation Epithelial cells
Online Access:	https://eprints.nottingham.ac.uk/27801/

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