Multiscale modelling of auxin transport in the plant-root elongation zone
In the root elongation zone of a plant, the hormone auxin moves in a polar manner due to active transport facilitated by spatially distributed influx and efflux carriers present on the cell membranes. To understand how the cell-scale active transport and passive diffusion combine to produce the effe...
| Main Authors: | , |
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| Format: | Article |
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Springer
2012
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| Online Access: | https://eprints.nottingham.ac.uk/2758/ |
| _version_ | 1848790868787462144 |
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| author | Band, Leah R. King, John R. |
| author_facet | Band, Leah R. King, John R. |
| author_sort | Band, Leah R. |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | In the root elongation zone of a plant, the hormone auxin moves in a polar manner due to active transport facilitated by spatially distributed influx and efflux carriers present on the cell membranes. To understand how the cell-scale active transport and passive diffusion combine to produce the effective tissue-scale flux, we apply asymptotic methods to a cell-based model of auxin transport to derive systematically a continuum description from the spatially discrete one. Using biologically relevant parameter values, we show how the carriers drive the dominant tissue-scale auxin flux and we predict how the overall auxin dynamics are affected by perturbations to these carriers, for example, in knockout mutants. The analysis shows how the dominant behaviour depends on the cells' lengths, and enables us to assess the relative importance of the diffusive auxin flux through the cell wall. Other distinguished limits are also identified and their potential roles discussed. As well as providing insight into auxin transport, the study illustrates the use of multiscale (cell to tissue) methods in deriving simplified models that retain the essential biology and provide understanding of the underlying dynamics. |
| first_indexed | 2025-11-14T18:19:27Z |
| format | Article |
| id | nottingham-2758 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T18:19:27Z |
| publishDate | 2012 |
| publisher | Springer |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-27582020-05-04T20:21:16Z https://eprints.nottingham.ac.uk/2758/ Multiscale modelling of auxin transport in the plant-root elongation zone Band, Leah R. King, John R. In the root elongation zone of a plant, the hormone auxin moves in a polar manner due to active transport facilitated by spatially distributed influx and efflux carriers present on the cell membranes. To understand how the cell-scale active transport and passive diffusion combine to produce the effective tissue-scale flux, we apply asymptotic methods to a cell-based model of auxin transport to derive systematically a continuum description from the spatially discrete one. Using biologically relevant parameter values, we show how the carriers drive the dominant tissue-scale auxin flux and we predict how the overall auxin dynamics are affected by perturbations to these carriers, for example, in knockout mutants. The analysis shows how the dominant behaviour depends on the cells' lengths, and enables us to assess the relative importance of the diffusive auxin flux through the cell wall. Other distinguished limits are also identified and their potential roles discussed. As well as providing insight into auxin transport, the study illustrates the use of multiscale (cell to tissue) methods in deriving simplified models that retain the essential biology and provide understanding of the underlying dynamics. Springer 2012-10 Article PeerReviewed Band, Leah R. and King, John R. (2012) Multiscale modelling of auxin transport in the plant-root elongation zone. Journal of Mathematical Biology, 65 (4). pp. 743-785. ISSN 0303-6812 http://link.springer.com/article/10.1007%2Fs00285-011-0472-y doi:10.1007/s00285-011-0472-y doi:10.1007/s00285-011-0472-y |
| spellingShingle | Band, Leah R. King, John R. Multiscale modelling of auxin transport in the plant-root elongation zone |
| title | Multiscale modelling of auxin transport in the plant-root elongation zone |
| title_full | Multiscale modelling of auxin transport in the plant-root elongation zone |
| title_fullStr | Multiscale modelling of auxin transport in the plant-root elongation zone |
| title_full_unstemmed | Multiscale modelling of auxin transport in the plant-root elongation zone |
| title_short | Multiscale modelling of auxin transport in the plant-root elongation zone |
| title_sort | multiscale modelling of auxin transport in the plant-root elongation zone |
| url | https://eprints.nottingham.ac.uk/2758/ https://eprints.nottingham.ac.uk/2758/ https://eprints.nottingham.ac.uk/2758/ |