Pulsed ultrasound modulated optical tomography with harmonic lock-in holography detection
A method that uses digital heterodyne holography reconstruction to extract scattered light modulated by a singlecycle ultrasound (US) burst is demonstrated and analyzed. An US burst is used to shift the pulsed laser frequency by a series of discrete harmonic frequencies which are then locked on a CC...
| Main Authors: | , , |
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| Format: | Article |
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Optical Society of America
2013
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| Online Access: | https://eprints.nottingham.ac.uk/2728/ |
| _version_ | 1848790860246810624 |
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| author | Ruan, Haowen Mather, Melissa Morgan, Stephen P. |
| author_facet | Ruan, Haowen Mather, Melissa Morgan, Stephen P. |
| author_sort | Ruan, Haowen |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | A method that uses digital heterodyne holography reconstruction to extract scattered light modulated by a singlecycle ultrasound (US) burst is demonstrated and analyzed. An US burst is used to shift the pulsed laser frequency by a series of discrete harmonic frequencies which are then locked on a CCD. The analysis demonstrates that the unmodulated light’s contribution to the detected signal can be canceled by appropriate selection of the pulse repetition frequency. It is also shown that the modulated signal can be maximized by selecting a pulse sequence which consists of a pulse followed by its inverted counterpart. The system is used to image a 12 mm thick chicken breast with 2 mm wide optically absorbing objects embedded at the midplane. Furthermore, the method can be
revised to detect the nonlinear US modulated signal by locking at the second harmonic US frequency. © 2013
Optical Society of America |
| first_indexed | 2025-11-14T18:19:19Z |
| format | Article |
| id | nottingham-2728 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T18:19:19Z |
| publishDate | 2013 |
| publisher | Optical Society of America |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-27282020-05-04T16:37:06Z https://eprints.nottingham.ac.uk/2728/ Pulsed ultrasound modulated optical tomography with harmonic lock-in holography detection Ruan, Haowen Mather, Melissa Morgan, Stephen P. A method that uses digital heterodyne holography reconstruction to extract scattered light modulated by a singlecycle ultrasound (US) burst is demonstrated and analyzed. An US burst is used to shift the pulsed laser frequency by a series of discrete harmonic frequencies which are then locked on a CCD. The analysis demonstrates that the unmodulated light’s contribution to the detected signal can be canceled by appropriate selection of the pulse repetition frequency. It is also shown that the modulated signal can be maximized by selecting a pulse sequence which consists of a pulse followed by its inverted counterpart. The system is used to image a 12 mm thick chicken breast with 2 mm wide optically absorbing objects embedded at the midplane. Furthermore, the method can be revised to detect the nonlinear US modulated signal by locking at the second harmonic US frequency. © 2013 Optical Society of America Optical Society of America 2013-07-01 Article PeerReviewed Ruan, Haowen, Mather, Melissa and Morgan, Stephen P. (2013) Pulsed ultrasound modulated optical tomography with harmonic lock-in holography detection. Journal of the Optical Society of America A, 30 (7). pp. 1409-1416. ISSN 1084-7529 http://www.opticsinfobase.org/josaa/abstract.cfm?uri=josaa-30-7-1409 doi:10.1364/JOSAA.30.001409 doi:10.1364/JOSAA.30.001409 |
| spellingShingle | Ruan, Haowen Mather, Melissa Morgan, Stephen P. Pulsed ultrasound modulated optical tomography with harmonic lock-in holography detection |
| title | Pulsed ultrasound modulated optical tomography with harmonic lock-in holography detection |
| title_full | Pulsed ultrasound modulated optical tomography with harmonic lock-in holography detection |
| title_fullStr | Pulsed ultrasound modulated optical tomography with harmonic lock-in holography detection |
| title_full_unstemmed | Pulsed ultrasound modulated optical tomography with harmonic lock-in holography detection |
| title_short | Pulsed ultrasound modulated optical tomography with harmonic lock-in holography detection |
| title_sort | pulsed ultrasound modulated optical tomography with harmonic lock-in holography detection |
| url | https://eprints.nottingham.ac.uk/2728/ https://eprints.nottingham.ac.uk/2728/ https://eprints.nottingham.ac.uk/2728/ |