Next generation sequencing of CLU, PICALM and CR1: pitfalls and potential solutions

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Next generation sequencing of CLU, PICALM and CR1: pitfalls and potential solutions

CLU, PICALM and CR1 were identified as genetic risk factors for late onset Alzheimer’s disease (AD) in two large genome wide association studies (GWAS) published in 2009, but the variants that convey this alteration in disease risk, and how the genes relate to AD pathology is yet to be discovered. A...

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Bibliographic Details
Main Authors:	Lord, Jenny, Turton, James, Medway, Christopher, Shi, Hui, Brown, Kristelle, Lowe, James, Mann, David, Pickering-Brown, Stuart, Kalsheker, Noor, Passmore, Peter, Morgan, Kevin
Format:	Article
Published:	e-Century Publishing 2012
Online Access:	https://eprints.nottingham.ac.uk/2696/

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