Leukotriene B4 receptor locus gene characterisation and association studies in asthma

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Leukotriene B4 receptor locus gene characterisation and association studies in asthma

Background: Polymorphisms spanning genes involved in the production of leukotriene B4 (LTB4) e.g. ALOX5AP and LTA4H are associated with asthma susceptibility, suggesting a role for LTB4 in disease. The contribution of LTB4 receptor polymorphism is currently unknown. The aim of this study was to ch...

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Bibliographic Details
Main Authors:	Tulah, Asif S., Beghé, Bianca, Barton, Sheila J., Holloway, John W., Sayers, Ian
Format:	Article
Published:	BioMed Central 2012
Subjects:	Association Asthma Family based association test Leukotriene Leukotriene B4 receptor Severity
Online Access:	https://eprints.nottingham.ac.uk/2625/

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