Statistical inference of in vivo properties of human
DNA methyltransferases from double-stranded
methylation patterns

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Statistical inference of in vivo properties of human DNA methyltransferases from double-stranded methylation patterns

DNA methyltransferases establish methylation patterns in cells and transmit these patterns over cell generations, thereby influencing each cell's epigenetic states. Three primary DNA methyltransferases have been identified in mammals: DNMT1, DNMT3A and DNMT3B. Extensive in vitro studies have in...

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Bibliographic Details
Main Authors:	Fu, Audrey Q., Genereux, Diane P., Stöger, Reinhard, Burden, Alice F., Laird, Charles D., Stephens, Matthew
Format:	Article
Published:	Public Library of Science 2012
Online Access:	https://eprints.nottingham.ac.uk/2604/

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