Effects of α-synuclein overexpression in transgenic Caenorhabditis elegans strains

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Effects of α-synuclein overexpression in transgenic Caenorhabditis elegans strains

The neural protein α-synuclein aggregates both in vivo and in vitro to form insoluble fibrils that are involved in Parkinson’s disease pathogenesis. We have generated α-synuclein/fluorescent-protein fusion constructs overexpressed in muscle cells of the nematode, Caenorhabdtis elegans. Green Fluore...

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Bibliographic Details
Main Authors:	Bodhicharla, Rakesh, Nagarajan, Archana, Winter, Jody, Adenle, Ademola, Nazir, Aamir, Brady, Declan, Vere, Kelly, Richens, Jo, O'Shea, Paul, Bell, David R., de Pomerai, David I.
Format:	Article
Published:	Bentham Science Publishers 2012
Subjects:	Caenorhabditis elegans CFP and YFP reporters FRET protein aggregation α-synuclein transgenic strains
Online Access:	https://eprints.nottingham.ac.uk/2591/

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