Effects of leucine and its metabolite β-hydroxy-β-methylbutyrate on human skeletal muscle protein metabolism
Maintenance of skeletal muscle mass is contingent upon the dynamic equilibrium (fasted losses–fed gains) in protein turnover. Of all nutrients, the single amino acid leucine (Leu) possesses the most marked anabolic characteristics in acting as a trigger element for the initiation of protein synthesi...
| Main Authors: | Wilkinson, D.J., Hossain, T., Hill, D.S., Phillips, B.E., Crossland, H., Williams, J., Loughna, P., Churchward-Venne, T.A., Breen, L., Phillips, S.M., Etheridge, T., Rathmacher, J.A., Smith, K., Szewczyk, N.J., Atherton, P.J. |
|---|---|
| Format: | Article |
| Published: |
Wiley
2013
|
| Online Access: | https://eprints.nottingham.ac.uk/2567/ |
Similar Items
Impact of the calcium form of β-hydroxy-β-methylbutyrate upon human skeletal muscle protein metabolism
by: Wilkinson, Daniel J., et al.
Published: (2017)
by: Wilkinson, Daniel J., et al.
Published: (2017)
Human skeletal muscle is refractory to the anabolic effects of leucine during the postprandial muscle-full period in older men
by: Mitchell, W. Kyle, et al.
Published: (2017)
by: Mitchell, W. Kyle, et al.
Published: (2017)
Insulin resistance in health and disease: exploring the role of disuse skeletal muscle atrophy, testosterone and Beta-Hydroxy-Beta-Methylbutyrate (HMB) in young and older men
by: Shanthaveerappa Rudrappa, Supreeth
Published: (2021)
by: Shanthaveerappa Rudrappa, Supreeth
Published: (2021)
Enriching a protein drink with leucine augments muscle protein synthesis after resistance exercise in young and older men
by: Atherton, Philip J., et al.
Published: (2016)
by: Atherton, Philip J., et al.
Published: (2016)
Effects of leucine-enriched essential amino acid and whey protein bolus dosing upon skeletal muscle protein synthesis at rest and after exercise in older women
by: Wilkinson, Daniel J., et al.
Published: (2017)
by: Wilkinson, Daniel J., et al.
Published: (2017)
Tunable pentapeptide self-assembled β-sheet hydrogels
by: Clarke, David E., et al.
Published: (2018)
by: Clarke, David E., et al.
Published: (2018)
Determination of Poly-β-Hydroxyalkanoate in peat
by: Dowrick, David J., et al.
Published: (2017)
by: Dowrick, David J., et al.
Published: (2017)
OTUD4 enhances TGFβ signalling through regulation of the TGFβ receptor complex
by: Jaynes, P.W., et al.
Published: (2020)
by: Jaynes, P.W., et al.
Published: (2020)
Synthesis and in vitro and in vivo characterization of highly β1-Selective β-Adrenoceptor partial agonists
by: Mistry, Shailesh N., et al.
Published: (2013)
by: Mistry, Shailesh N., et al.
Published: (2013)
The impact of leucine-enriched whey protein on skeletal muscle anabolism
by: Ely, Isabel
Published: (2024)
by: Ely, Isabel
Published: (2024)
Monoclonal anti-β1-adrenergic receptor antibodies activate G protein signaling in the absence of β-arrestin recruitment
by: Hutchings, Catherine J., et al.
Published: (2013)
by: Hutchings, Catherine J., et al.
Published: (2013)
Application of novel deuterium oxide tracer techniques to determine the effects of ß-hydroxy ß-methylbutyrate (HMB) supplementation and exercise in ageing: a randomized placebo controlled trial
by: Din, Ushnah Shujah Ud
Published: (2016)
by: Din, Ushnah Shujah Ud
Published: (2016)
GSK-3β phosphorylation and alteration of β-catenin in hepatocellular carcinoma
by: Ban, Ke Chen, et al.
Published: (2003)
by: Ban, Ke Chen, et al.
Published: (2003)
Predicting β-turns and their types using predicted backbone dihedral angles and secondary structures
by: Kountouris, Peter, et al.
Published: (2010)
by: Kountouris, Peter, et al.
Published: (2010)
The metabolic and molecular mechanisms of hyperammonaemia and hyperethanolaemia induced protein catabolism in skeletal muscle cells
by: Crossland, Hannah, et al.
Published: (2018)
by: Crossland, Hannah, et al.
Published: (2018)
A novel puromycin decorporation method to quantify skeletal muscle protein breakdown: a proof-of-concept study
by: Crossland, Hannah, et al.
Published: (2017)
by: Crossland, Hannah, et al.
Published: (2017)
Applying neutral drift to the directed molecular evolution of a β-glucuronidase into a β-galactosidase: Two different evolutionary pathways lead to the same variant
by: Smith, W.S., et al.
Published: (2011)
by: Smith, W.S., et al.
Published: (2011)
Haplotype analysis of β-Thalassaemia major and carriers with Filipino β°-deletion in Sabah, Malaysia
by: Teh, Lai Kuan, et al.
Published: (2018)
by: Teh, Lai Kuan, et al.
Published: (2018)
Effect Of Aging Time, Calcination And Sintering Temperature To Β-Tricalcium Phosphate (Β-Tcp)
by: Redin, Hanna Bakar
Published: (2019)
by: Redin, Hanna Bakar
Published: (2019)
Evolution of β-blockers: from anti-anginal drugs to
ligand-directed signalling
by: Baker, Jillian G., et al.
Published: (2011)
by: Baker, Jillian G., et al.
Published: (2011)
A direct calibration of thtae IRX–β relation in Lyman-break galaxies at z=3–5
by: Koprowski, M.P., et al.
Published: (2018)
by: Koprowski, M.P., et al.
Published: (2018)
Complexing of chlorogenic acid with β-cyclodextrins: Inclusion effects, antioxidative properties and potential application in grape juice
by: Shao, P., et al.
Published: (2014)
by: Shao, P., et al.
Published: (2014)
Analysis on the AAβ cryptosystem
by: Asbullah, Muhammad Asyraf, et al.
Published: (2016)
by: Asbullah, Muhammad Asyraf, et al.
Published: (2016)
Asymptomatic neurotoxicity of amyloid β-peptides (Aβ1-42 and Aβ25-35) on mouse embryonic stem cell-derived neural cells
by: Mansor, Nur Izzati, et al.
Published: (2020)
by: Mansor, Nur Izzati, et al.
Published: (2020)
A critical role for cystathionine-β-synthase in hydrogen sulfide-mediated hypoxic relaxation of the coronary artery
by: Donovan, J., et al.
Published: (2017)
by: Donovan, J., et al.
Published: (2017)
Immobilization of escherichia coli producing β-cyclodextrin glucanotransferase on hollow fiber membrane for β-cyclodextrin production
by: Nurul Nabila Huda, Baharudin
Published: (2023)
by: Nurul Nabila Huda, Baharudin
Published: (2023)
Novel selective β1-adrenoceptor antagonists for concomitant cardiovascular and respiratory disease
by: Baker, Jillian G., et al.
Published: (2017)
by: Baker, Jillian G., et al.
Published: (2017)
Differential effects of short-term β agonist and growth hormone treatments on expression of myosin heavy chain IIB and associated metabolic genes in sheep muscle
by: Hemmings, K.M., et al.
Published: (2014)
by: Hemmings, K.M., et al.
Published: (2014)
Relationship between surface concentration of l-leucine and bulk powder properties in spray dried formulations
by: Mangal, S., et al.
Published: (2015)
by: Mangal, S., et al.
Published: (2015)
Escherichia coli glucuronylsynthase: an engineered enzyme for the synthesis of β-glucuronides
by: Wilkinson, Shane M., et al.
Published: (2008)
by: Wilkinson, Shane M., et al.
Published: (2008)
The Influence of Cholesterol on β-cell Function
by: Ellison, Gaewyn Colleen
Published: (2019)
by: Ellison, Gaewyn Colleen
Published: (2019)
Algebraic cryptanalysis on the AAβ cryptosystem
by: Asbullah, Muhammad Asyraf, et al.
Published: (2017)
by: Asbullah, Muhammad Asyraf, et al.
Published: (2017)
Enhanced AAβ cryptosystem: the design
by: Asbullah, Muhammad Asyraf, et al.
Published: (2018)
by: Asbullah, Muhammad Asyraf, et al.
Published: (2018)
The role of TGFβ in human cancers
by: Wong, Shew-Fung, et al.
Published: (2001)
by: Wong, Shew-Fung, et al.
Published: (2001)
β-Cyclodextrin/lecithin: preparation and characterization
by: Eng, Hui Peng, et al.
Published: (2017)
by: Eng, Hui Peng, et al.
Published: (2017)
HbA2 levels in β-thalassaemia carriers with the Filipino β0-deletion: are the levels higher than what is found with non-deletional forms of β0-thalassaemia?
by: George, Elizabeth, et al.
Published: (2013)
by: George, Elizabeth, et al.
Published: (2013)
The apoptotic analysis of 7α-hydroxy-β-sitosterol extracted from Chisocheton tomentosus (Meliaceae) in cancer cell lines / Mohammad Tasyriq bin Che Omar
by: Che Omar, Mohammad Tasyriq
Published: (2012)
by: Che Omar, Mohammad Tasyriq
Published: (2012)
Insulinotropic activity of Tinospora crispa extract: effect on β-cell Ca2+ handling
by: Noor, Hamdan, et al.
Published: (1998)
by: Noor, Hamdan, et al.
Published: (1998)
Tgf-β stimulated glycosaminoglycan (GAG) biosynthetic gene expression in vascular smooth muscle cells
by: Rostam, Muhamad Ashraf, et al.
Published: (2013)
by: Rostam, Muhamad Ashraf, et al.
Published: (2013)
Stereoselective synthesis of functionalized pyrrolidines by the diverted NH insertion reaction of metallocarbenes with β-aminoketone derivatives
by: Nicolle, Simon M., et al.
Published: (2016)
by: Nicolle, Simon M., et al.
Published: (2016)
Similar Items
-
Impact of the calcium form of β-hydroxy-β-methylbutyrate upon human skeletal muscle protein metabolism
by: Wilkinson, Daniel J., et al.
Published: (2017) -
Human skeletal muscle is refractory to the anabolic effects of leucine during the postprandial muscle-full period in older men
by: Mitchell, W. Kyle, et al.
Published: (2017) -
Insulin resistance in health and disease: exploring the role of disuse skeletal muscle atrophy, testosterone and Beta-Hydroxy-Beta-Methylbutyrate (HMB) in young and older men
by: Shanthaveerappa Rudrappa, Supreeth
Published: (2021) -
Enriching a protein drink with leucine augments muscle protein synthesis after resistance exercise in young and older men
by: Atherton, Philip J., et al.
Published: (2016) -
Effects of leucine-enriched essential amino acid and whey protein bolus dosing upon skeletal muscle protein synthesis at rest and after exercise in older women
by: Wilkinson, Daniel J., et al.
Published: (2017)