The role of proton dynamics in the development and maintenance of multidrug resistance in cancer

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The role of proton dynamics in the development and maintenance of multidrug resistance in cancer

With a projected 382.4 per 100,000 people expected to suffer from some form of malignant neoplasm in 2015, improving treatment is an essential focus of cancer research today. Multi-drug resistance (MDR) is the leading cause of chemotherapeutic failure in the treatment of cancer, the term denoting a...

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Bibliographic Details
Main Authors:	Daniel, Chloë, Bell, Charlotte, Burton, Christopher, Harguindey, Salvador, Reshkinc, Stephan J., Rauch, Cyril
Format:	Article
Published:	Elsevier 2013
Subjects:	Multidrug resistance; Proton pump; Cancer; Drug efflux; Membrane physical biology
Online Access:	https://eprints.nottingham.ac.uk/2531/

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