High-resolution replication profiles define the stochastic nature of genome replication initiation and termination

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High-resolution replication profiles define the stochastic nature of genome replication initiation and termination

Eukaryotic genome replication is stochastic, and each cell uses a different cohort of replication origins. We demonstrate that interpreting high-resolution Saccharomyces cerevisiae genome replication data with a mathematical model allows quantification of the stochastic nature of genome replication,...

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Bibliographic Details
Main Authors:	Hawkins, Michelle, Retkute, Renata, Müller, Carolin A., Saner, Nazan, Tanaka, Tomoyuki U., de Moura, Alessandro P.S., Nieduszynski, Conrad A.
Format:	Article
Published:	Elsevier 2013
Online Access:	https://eprints.nottingham.ac.uk/2525/

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