Characterisation of a group of endogenous gammaretroviruses in the canine genome

Bioinformatics were used to identify and characterise 39 pol, 34 gag and five env gammaretroviruses within the canine (Canis lupus familiaris) reference genome. These endogenous retroviruses are monophyletic to the Canidae, predate the divergence of dogs and foxes and are fixed in 20 canine breeds e...

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Main Authors: Tarlinton, Rachael E., Barfoot, Hannah K.R., Allen, Ceri E., Brown, Katherine, Gifford, Robert J., Emes, Richard D.
Format: Article
Published: Elsevier 2013
Subjects:
Online Access:https://eprints.nottingham.ac.uk/2476/
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author Tarlinton, Rachael E.
Barfoot, Hannah K.R.
Allen, Ceri E.
Brown, Katherine
Gifford, Robert J.
Emes, Richard D.
author_facet Tarlinton, Rachael E.
Barfoot, Hannah K.R.
Allen, Ceri E.
Brown, Katherine
Gifford, Robert J.
Emes, Richard D.
author_sort Tarlinton, Rachael E.
building Nottingham Research Data Repository
collection Online Access
description Bioinformatics were used to identify and characterise 39 pol, 34 gag and five env gammaretroviruses within the canine (Canis lupus familiaris) reference genome. These endogenous retroviruses are monophyletic to the Canidae, predate the divergence of dogs and foxes and are fixed in 20 canine breeds examined. They are transcribed in normal canine tissue but are unlikely to be replication competent in dogs.
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publishDate 2013
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spelling nottingham-24762020-05-04T20:19:29Z https://eprints.nottingham.ac.uk/2476/ Characterisation of a group of endogenous gammaretroviruses in the canine genome Tarlinton, Rachael E. Barfoot, Hannah K.R. Allen, Ceri E. Brown, Katherine Gifford, Robert J. Emes, Richard D. Bioinformatics were used to identify and characterise 39 pol, 34 gag and five env gammaretroviruses within the canine (Canis lupus familiaris) reference genome. These endogenous retroviruses are monophyletic to the Canidae, predate the divergence of dogs and foxes and are fixed in 20 canine breeds examined. They are transcribed in normal canine tissue but are unlikely to be replication competent in dogs. Elsevier 2013-04 Article PeerReviewed Tarlinton, Rachael E., Barfoot, Hannah K.R., Allen, Ceri E., Brown, Katherine, Gifford, Robert J. and Emes, Richard D. (2013) Characterisation of a group of endogenous gammaretroviruses in the canine genome. Veterinary Journal, 196 (1). pp. 28-33. ISSN 1090-0233 Canine Endogenous retroviruses Gammaretroviruses http://www.sciencedirect.com/science/article/pii/S1090023312003528 doi:10.1016/j.tvjl.2012.08.011 doi:10.1016/j.tvjl.2012.08.011
spellingShingle Canine
Endogenous retroviruses
Gammaretroviruses
Tarlinton, Rachael E.
Barfoot, Hannah K.R.
Allen, Ceri E.
Brown, Katherine
Gifford, Robert J.
Emes, Richard D.
Characterisation of a group of endogenous gammaretroviruses in the canine genome
title Characterisation of a group of endogenous gammaretroviruses in the canine genome
title_full Characterisation of a group of endogenous gammaretroviruses in the canine genome
title_fullStr Characterisation of a group of endogenous gammaretroviruses in the canine genome
title_full_unstemmed Characterisation of a group of endogenous gammaretroviruses in the canine genome
title_short Characterisation of a group of endogenous gammaretroviruses in the canine genome
title_sort characterisation of a group of endogenous gammaretroviruses in the canine genome
topic Canine
Endogenous retroviruses
Gammaretroviruses
url https://eprints.nottingham.ac.uk/2476/
https://eprints.nottingham.ac.uk/2476/
https://eprints.nottingham.ac.uk/2476/