Structural basis for native agonist and synthetic inhibitor recognition by the Pseudomonas aeruginosa quorum sensing regulator PqsR (MvfR)

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Structural basis for native agonist and synthetic inhibitor recognition by the Pseudomonas aeruginosa quorum sensing regulator PqsR (MvfR)

Bacterial populations co-ordinate gene expression collectively through quorum sensing (QS), a cell-to-cell communication mechanism employing diffusible signal molecules. The LysR-type transcriptional regulator (LTTR) protein PqsR (MvfR) is a key component of alkyl-quinolone (AQ)-dependent QS in Pseu...

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Bibliographic Details
Main Authors:	Ilangovan, Aravindan, Fletcher, Matthew, Rampioni, Giordano, Pustelny, Christian, Rumbaugh, Kendra, Heeb, Stephan, Cámara, Miguel, Truman, Alex, Chhabra, Siri Ram, Emsley, Jonas, Williams, Paul
Format:	Article
Published:	Public Library of Science 2013
Online Access:	https://eprints.nottingham.ac.uk/2418/

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