Event-related fMRI at 7T reveals overlapping cortical representations for adjacent fingertips in S1 of individual subjects
Recent fMRI studies of the human primary somatosensory cortex have been able to differentiate the cortical representations of different fingertips at a single-subject level. These studies did not, however, investigate the expected overlap in cortical activation due to the stimulation of different fi...
| Main Authors: | , , , , |
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| Format: | Article |
| Published: |
Wiley
2013
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| Online Access: | https://eprints.nottingham.ac.uk/2401/ |
| _version_ | 1848790775841685504 |
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| author | Besle, Julien Sánchez-Panchuelo, Rosa-Maria Bowtell, Richard Francis, Susan Schluppeck, Denis |
| author_facet | Besle, Julien Sánchez-Panchuelo, Rosa-Maria Bowtell, Richard Francis, Susan Schluppeck, Denis |
| author_sort | Besle, Julien |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Recent fMRI studies of the human primary somatosensory cortex have been able to differentiate the cortical representations of different fingertips at a single-subject level. These studies did not, however, investigate the expected overlap in cortical activation due to the stimulation of different fingers. Here, we used an event-related design in six subjects at 7 Tesla to explore the overlap in cortical responses elicited in S1 by vibrotactile stimulation of the five fingertips. We found that all parts of S1 show some degree of spatial overlap between the cortical representations of adjacent or even nonadjacent fingertips. In S1, the posterior bank of the central sulcus showed less overlap than regions in the post-central gyrus, which responded to up to five fingertips. The functional properties of these two areas are consistent with the known layout of cytoarchitectonically defined subareas, and we speculate that they correspond to subarea 3b (S1 proper) and subarea 1, respectively. In contrast with previous fMRI studies, however, we did not observe discrete activation clusters that could unequivocally be attributed to different subareas of S1. Venous maps based on T2*-weighted structural images suggest that the observed overlap is not driven by extra-vascular contributions from large veins |
| first_indexed | 2025-11-14T18:17:59Z |
| format | Article |
| id | nottingham-2401 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T18:17:59Z |
| publishDate | 2013 |
| publisher | Wiley |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-24012020-05-04T16:38:58Z https://eprints.nottingham.ac.uk/2401/ Event-related fMRI at 7T reveals overlapping cortical representations for adjacent fingertips in S1 of individual subjects Besle, Julien Sánchez-Panchuelo, Rosa-Maria Bowtell, Richard Francis, Susan Schluppeck, Denis Recent fMRI studies of the human primary somatosensory cortex have been able to differentiate the cortical representations of different fingertips at a single-subject level. These studies did not, however, investigate the expected overlap in cortical activation due to the stimulation of different fingers. Here, we used an event-related design in six subjects at 7 Tesla to explore the overlap in cortical responses elicited in S1 by vibrotactile stimulation of the five fingertips. We found that all parts of S1 show some degree of spatial overlap between the cortical representations of adjacent or even nonadjacent fingertips. In S1, the posterior bank of the central sulcus showed less overlap than regions in the post-central gyrus, which responded to up to five fingertips. The functional properties of these two areas are consistent with the known layout of cytoarchitectonically defined subareas, and we speculate that they correspond to subarea 3b (S1 proper) and subarea 1, respectively. In contrast with previous fMRI studies, however, we did not observe discrete activation clusters that could unequivocally be attributed to different subareas of S1. Venous maps based on T2*-weighted structural images suggest that the observed overlap is not driven by extra-vascular contributions from large veins Wiley 2013-09-03 Article PeerReviewed Besle, Julien, Sánchez-Panchuelo, Rosa-Maria, Bowtell, Richard, Francis, Susan and Schluppeck, Denis (2013) Event-related fMRI at 7T reveals overlapping cortical representations for adjacent fingertips in S1 of individual subjects. Human Brain Mapping . ISSN 1065-9471 http://onlinelibrary.wiley.com/doi/10.1002/hbm.22310/abstract doi:10.1002/hbm.22310 doi:10.1002/hbm.22310 |
| spellingShingle | Besle, Julien Sánchez-Panchuelo, Rosa-Maria Bowtell, Richard Francis, Susan Schluppeck, Denis Event-related fMRI at 7T reveals overlapping cortical representations for adjacent fingertips in S1 of individual subjects |
| title | Event-related fMRI at 7T reveals overlapping cortical representations for adjacent fingertips in S1 of individual subjects |
| title_full | Event-related fMRI at 7T reveals overlapping cortical representations for adjacent fingertips in S1 of individual subjects |
| title_fullStr | Event-related fMRI at 7T reveals overlapping cortical representations for adjacent fingertips in S1 of individual subjects |
| title_full_unstemmed | Event-related fMRI at 7T reveals overlapping cortical representations for adjacent fingertips in S1 of individual subjects |
| title_short | Event-related fMRI at 7T reveals overlapping cortical representations for adjacent fingertips in S1 of individual subjects |
| title_sort | event-related fmri at 7t reveals overlapping cortical representations for adjacent fingertips in s1 of individual subjects |
| url | https://eprints.nottingham.ac.uk/2401/ https://eprints.nottingham.ac.uk/2401/ https://eprints.nottingham.ac.uk/2401/ |