Hepatitis C virus envelope glycoprotein fitness defines virus population composition following transmission to a new host

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Hepatitis C virus envelope glycoprotein fitness defines virus population composition following transmission to a new host

Genetic variability is a hallmark of RNA virus populations. However, transmission to a new host often results in a marked decrease in population diversity. This genetic bottlenecking is observed during hepatitis C virus (HCV) transmission and can arise via a selective sweep or through the founder ef...

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Bibliographic Details
Main Authors:	Brown, Richard J.P., Hudson, Natalia, Wilson, Garrick, Rehman, Shafiq Ur, Jabbari, Sara, Hu, Ke, Tarr, Alexander W., Borrow, Persephone, Joyce, Michael, Lewis, Jamie, Zhu, Lin Fu, Law, Mansun, Kneteman, Norman, Tyrrell, D. Lorne, McKeating, Jane A., Ball, Jonathan K.
Format:	Article
Published:	American Society for Microbiology 2012
Online Access:	https://eprints.nottingham.ac.uk/2387/

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