Systematic review and meta-analyses of risk factors for childhood overweight identifiable during infancy

Objective To determine risk factors for childhood overweight that can be identified during the first year of life to facilitate early identification and targeted intervention. Design Systematic review and meta-analysis. Search strategy Electronic database search of MEDLINE, EMBASE, PubMed and...

Full description

Bibliographic Details
Main Authors: Weng, Stephen Franklin, Redsell, Sarah A., Swift, Judy A., Yang, Min, Glazebrook, Cristine P.
Format: Article
Published: BMJ Group 2012
Online Access:https://eprints.nottingham.ac.uk/2320/
_version_ 1848790754294497280
author Weng, Stephen Franklin
Redsell, Sarah A.
Swift, Judy A.
Yang, Min
Glazebrook, Cristine P.
author_facet Weng, Stephen Franklin
Redsell, Sarah A.
Swift, Judy A.
Yang, Min
Glazebrook, Cristine P.
author_sort Weng, Stephen Franklin
building Nottingham Research Data Repository
collection Online Access
description Objective To determine risk factors for childhood overweight that can be identified during the first year of life to facilitate early identification and targeted intervention. Design Systematic review and meta-analysis. Search strategy Electronic database search of MEDLINE, EMBASE, PubMed and CAB Abstracts. Eligibility criteria Prospective observational studies following up children from birth for at least 2 years. Results Thirty prospective studies were identified. Significant and strong independent associations with childhood overweight were identified for maternal prepregnancy overweight, high infant birth weight and rapid weight gain during the first year of life. Meta-analysis comparing breastfed with non-breastfed infants found a 15% decrease (95% CI 0.74 to 0.99; I2=73.3%; n=10) in the odds of childhood overweight. For children of mothers smoking during pregnancy there was a 47% increase (95% CI 1.26 to 1.73; I2=47.5%; n=7) in the odds of childhood overweight. There was some evidence associating early introduction of solid foods and childhood overweight. There was conflicting evidence for duration of breastfeeding, socioeconomic status at birth, parity and maternal marital status at birth. No association with childhood overweight was found for maternal age or education at birth, maternal depression or infant ethnicity. There was inconclusive evidence for delivery type, gestational weight gain, maternal postpartum weight loss and ‘fussy’ infant temperament due to the limited number of studies. Conclusions Several risk factors for both overweight and obesity in childhood are identifiable during infancy. Future research needs to focus on whether it is clinically feasible for healthcare professionals to identify infants at greatest risk.
first_indexed 2025-11-14T18:17:38Z
format Article
id nottingham-2320
institution University of Nottingham Malaysia Campus
institution_category Local University
last_indexed 2025-11-14T18:17:38Z
publishDate 2012
publisher BMJ Group
recordtype eprints
repository_type Digital Repository
spelling nottingham-23202020-05-04T16:34:22Z https://eprints.nottingham.ac.uk/2320/ Systematic review and meta-analyses of risk factors for childhood overweight identifiable during infancy Weng, Stephen Franklin Redsell, Sarah A. Swift, Judy A. Yang, Min Glazebrook, Cristine P. Objective To determine risk factors for childhood overweight that can be identified during the first year of life to facilitate early identification and targeted intervention. Design Systematic review and meta-analysis. Search strategy Electronic database search of MEDLINE, EMBASE, PubMed and CAB Abstracts. Eligibility criteria Prospective observational studies following up children from birth for at least 2 years. Results Thirty prospective studies were identified. Significant and strong independent associations with childhood overweight were identified for maternal prepregnancy overweight, high infant birth weight and rapid weight gain during the first year of life. Meta-analysis comparing breastfed with non-breastfed infants found a 15% decrease (95% CI 0.74 to 0.99; I2=73.3%; n=10) in the odds of childhood overweight. For children of mothers smoking during pregnancy there was a 47% increase (95% CI 1.26 to 1.73; I2=47.5%; n=7) in the odds of childhood overweight. There was some evidence associating early introduction of solid foods and childhood overweight. There was conflicting evidence for duration of breastfeeding, socioeconomic status at birth, parity and maternal marital status at birth. No association with childhood overweight was found for maternal age or education at birth, maternal depression or infant ethnicity. There was inconclusive evidence for delivery type, gestational weight gain, maternal postpartum weight loss and ‘fussy’ infant temperament due to the limited number of studies. Conclusions Several risk factors for both overweight and obesity in childhood are identifiable during infancy. Future research needs to focus on whether it is clinically feasible for healthcare professionals to identify infants at greatest risk. BMJ Group 2012-10-29 Article PeerReviewed Weng, Stephen Franklin, Redsell, Sarah A., Swift, Judy A., Yang, Min and Glazebrook, Cristine P. (2012) Systematic review and meta-analyses of risk factors for childhood overweight identifiable during infancy. Archives of Disease in Childhood, 97 (12). pp. 1019-1026. ISSN 0003-9888 http://adc.bmj.com/content/97/12/1019 doi:10.1136/archdischild-2012-302263 doi:10.1136/archdischild-2012-302263
spellingShingle Weng, Stephen Franklin
Redsell, Sarah A.
Swift, Judy A.
Yang, Min
Glazebrook, Cristine P.
Systematic review and meta-analyses of risk factors for childhood overweight identifiable during infancy
title Systematic review and meta-analyses of risk factors for childhood overweight identifiable during infancy
title_full Systematic review and meta-analyses of risk factors for childhood overweight identifiable during infancy
title_fullStr Systematic review and meta-analyses of risk factors for childhood overweight identifiable during infancy
title_full_unstemmed Systematic review and meta-analyses of risk factors for childhood overweight identifiable during infancy
title_short Systematic review and meta-analyses of risk factors for childhood overweight identifiable during infancy
title_sort systematic review and meta-analyses of risk factors for childhood overweight identifiable during infancy
url https://eprints.nottingham.ac.uk/2320/
https://eprints.nottingham.ac.uk/2320/
https://eprints.nottingham.ac.uk/2320/