A beginner's guide to systems simulation in immunology

Some common systems modelling and simulation approaches for immune problems are Monte Carlo simulations, system dynamics, discrete-event simulation and agent-based simulation. These methods, however, are still not widely adopted in immunology research. In addition, to our knowledge, there is few res...

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Main Authors: Figueredo, Grazziela P., Siebers, Peer-Olaf, Aickelin, Uwe, Foan, Stephanie
Other Authors: Coello Coello, Carlos A.
Format: Book Section
Published: Springer 2012
Online Access:https://eprints.nottingham.ac.uk/2032/
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author Figueredo, Grazziela P.
Siebers, Peer-Olaf
Aickelin, Uwe
Foan, Stephanie
author2 Coello Coello, Carlos A.
author_facet Coello Coello, Carlos A.
Figueredo, Grazziela P.
Siebers, Peer-Olaf
Aickelin, Uwe
Foan, Stephanie
author_sort Figueredo, Grazziela P.
building Nottingham Research Data Repository
collection Online Access
description Some common systems modelling and simulation approaches for immune problems are Monte Carlo simulations, system dynamics, discrete-event simulation and agent-based simulation. These methods, however, are still not widely adopted in immunology research. In addition, to our knowledge, there is few research on the processes for the development of simulation models for the immune system. Hence, for this work, we have two contributions to knowledge. The first one is to show the importance of systems simulation to help immunological research and to draw the attention of simulation developers to this research field. The second contribution is the introduction of a quick guide containing the main steps for modelling and simulation in immunology, together with challenges that occur during the model development. Further, this paper introduces an example of a simulation problem, where we test our guidelines.
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institution University of Nottingham Malaysia Campus
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spelling nottingham-20322020-05-04T20:22:29Z https://eprints.nottingham.ac.uk/2032/ A beginner's guide to systems simulation in immunology Figueredo, Grazziela P. Siebers, Peer-Olaf Aickelin, Uwe Foan, Stephanie Some common systems modelling and simulation approaches for immune problems are Monte Carlo simulations, system dynamics, discrete-event simulation and agent-based simulation. These methods, however, are still not widely adopted in immunology research. In addition, to our knowledge, there is few research on the processes for the development of simulation models for the immune system. Hence, for this work, we have two contributions to knowledge. The first one is to show the importance of systems simulation to help immunological research and to draw the attention of simulation developers to this research field. The second contribution is the introduction of a quick guide containing the main steps for modelling and simulation in immunology, together with challenges that occur during the model development. Further, this paper introduces an example of a simulation problem, where we test our guidelines. Springer Coello Coello, Carlos A. Greensmith, Julie Krasnogor, Natalio Liò, P. Nicosia, G. Pavone, M. 2012 Book Section PeerReviewed Figueredo, Grazziela P., Siebers, Peer-Olaf, Aickelin, Uwe and Foan, Stephanie (2012) A beginner's guide to systems simulation in immunology. In: Artificial immune systems: 11th International Conference, ICARIS 2012, Taormina, Italy, August 28-31, 2012: proceedings. Lecture notes in computer science (7597). Springer, Berlin, pp. 57-71. ISBN 9783642337574 http://www.springer.com/computer/theoretical+computer+science/book/978-3-642-33756-7
spellingShingle Figueredo, Grazziela P.
Siebers, Peer-Olaf
Aickelin, Uwe
Foan, Stephanie
A beginner's guide to systems simulation in immunology
title A beginner's guide to systems simulation in immunology
title_full A beginner's guide to systems simulation in immunology
title_fullStr A beginner's guide to systems simulation in immunology
title_full_unstemmed A beginner's guide to systems simulation in immunology
title_short A beginner's guide to systems simulation in immunology
title_sort beginner's guide to systems simulation in immunology
url https://eprints.nottingham.ac.uk/2032/
https://eprints.nottingham.ac.uk/2032/