Systems dynamics or agent-based modelling for immune simulation?

In immune system simulation there are two competing simulation approaches: System Dynamics Simulation (SDS) and Agent-Based Simulation (ABS). In the literature there is little guidance on how to choose the best approach for a specific immune problem. Our overall research aim is to develop a framewor...

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Main Authors: Figueredo, Grazziela P., Aickelin, Uwe, Siebers, Peer-Olaf
Other Authors: Liò, Pietro
Format: Book Section
Published: Springer 2011
Online Access:https://eprints.nottingham.ac.uk/2030/
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author Figueredo, Grazziela P.
Aickelin, Uwe
Siebers, Peer-Olaf
author2 Liò, Pietro
author_facet Liò, Pietro
Figueredo, Grazziela P.
Aickelin, Uwe
Siebers, Peer-Olaf
author_sort Figueredo, Grazziela P.
building Nottingham Research Data Repository
collection Online Access
description In immune system simulation there are two competing simulation approaches: System Dynamics Simulation (SDS) and Agent-Based Simulation (ABS). In the literature there is little guidance on how to choose the best approach for a specific immune problem. Our overall research aim is to develop a framework that helps researchers with this choice. In this paper we investigate if it is possible to easily convert simulationmodels between approaches. With no explicit guidelines available fromthe literature we develop and test our own set of guidelines for convertingSDS models into ABS models in a non-spacial scenario. We also define guidelines to convert ABS into SDS considering a non-spatial and a spatial scenario. After running some experiments with the developed models we found that in all cases there are significant differences between the results produced by the different simulation methods.
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institution University of Nottingham Malaysia Campus
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publishDate 2011
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spelling nottingham-20302024-11-08T14:54:19Z https://eprints.nottingham.ac.uk/2030/ Systems dynamics or agent-based modelling for immune simulation? Figueredo, Grazziela P. Aickelin, Uwe Siebers, Peer-Olaf In immune system simulation there are two competing simulation approaches: System Dynamics Simulation (SDS) and Agent-Based Simulation (ABS). In the literature there is little guidance on how to choose the best approach for a specific immune problem. Our overall research aim is to develop a framework that helps researchers with this choice. In this paper we investigate if it is possible to easily convert simulationmodels between approaches. With no explicit guidelines available fromthe literature we develop and test our own set of guidelines for convertingSDS models into ABS models in a non-spacial scenario. We also define guidelines to convert ABS into SDS considering a non-spatial and a spatial scenario. After running some experiments with the developed models we found that in all cases there are significant differences between the results produced by the different simulation methods. Springer Liò, Pietro Nicosia, Giuseppe Stibor, Thomas 2011 Book Section PeerReviewed Figueredo, Grazziela P., Aickelin, Uwe and Siebers, Peer-Olaf (2011) Systems dynamics or agent-based modelling for immune simulation? In: Artificial immune systems: 10th international conference, ICARIS 2011, Cambridge, UK, July 18-21, 2011: proceedings. Lecture notes in computer science (6825). Springer, Heidelberg, pp. 81-94. ISBN 9783642223716 http://link.springer.com/chapter/10.1007/978-3-642-22371-6_10 https://doi.org/10.1007/978-3-642-22371-6_10 https://doi.org/10.1007/978-3-642-22371-6_10
spellingShingle Figueredo, Grazziela P.
Aickelin, Uwe
Siebers, Peer-Olaf
Systems dynamics or agent-based modelling for immune simulation?
title Systems dynamics or agent-based modelling for immune simulation?
title_full Systems dynamics or agent-based modelling for immune simulation?
title_fullStr Systems dynamics or agent-based modelling for immune simulation?
title_full_unstemmed Systems dynamics or agent-based modelling for immune simulation?
title_short Systems dynamics or agent-based modelling for immune simulation?
title_sort systems dynamics or agent-based modelling for immune simulation?
url https://eprints.nottingham.ac.uk/2030/
https://eprints.nottingham.ac.uk/2030/
https://eprints.nottingham.ac.uk/2030/