Molecular dynamics simulations and in silico peptide ligand screening of the Elk-1 ETS domain

QR Code

Molecular dynamics simulations and in silico peptide ligand screening of the Elk-1 ETS domain

Background: The Elk-1 transcription factor is a member of a group of proteins called ternary complex factors, which serve as a paradigm for gene regulation in response to extracellular signals. Its deregulation has been linked to multiple human diseases including the development of tumours. The wor...

Full description

Bibliographic Details
Main Authors:	Hussain, A., Shaw, P.E., Hirst, J.D.
Format:	Article
Published:	2011
Online Access:	https://eprints.nottingham.ac.uk/1948/

Similar Items

Molecular dynamics simulations using graphics processing units
by: Baker, J.A., et al.
Published: (2011)

Stepwise evolution of Elk-1 in early deuterostomes
by: Saxton, Janice, et al.
Published: (2016)

Docking and molecular dynamics simulations of the ternary complex nisin2:lipid II
by: Mulholland, Sam, et al.
Published: (2016)

The role of monoubiquitylation in the regulation of the transcription factor Elk-1
by: Chow, Kam Yuen
Published: (2011)

Molecular simulation of protein-ligand complexes
by: Guest, Ellen
Published: (2022)

Molecular simulations and visualization: introduction and overview
by: Hirst, J.D., et al.
Published: (2014)

Molecular Dynamics Simulation of the Permeation of Lipid- Conjugated Peptides through the Stratum Corneum
by: Ruiz Perez, Lanie
Published: (2021)

Simulation of the two-dimensional infrared spectroscopy of peptides using localized normal modes
by: Hanson-Heine, Magnus W.D., et al.
Published: (2016)

Molecular dynamics simulation of the phosphorylation-induced conformational changes of a tau peptide fragment
by: Lyons, Albert, et al.
Published: (2014)

The regulatory role of ELK-1 ubiquitination in cell proliferation and prostate cancer
by: Quintero Barceinas, Reyna Sara
Published: (2020)

In Silico And In Vitro Characterisation Of Peptide Binding Sequence Of Trim25 Cc Domain Towards 14-3-3 Sigma Protein
by: Chiang, De Chen
Published: (2023)

Probing polyoxometalate-protein interactions using molecular dynamics simulations
by: Solé-Daura, Albert, et al.
Published: (2016)

ERK phosphorylation of MED14 in promoter complexes during mitogen-induced gene activation by Elk-1
by: Galbraith, Matthew D., et al.
Published: (2013)

New CHARMM force field parameters for dehydrated amino acid residues, the key to lantibiotic molecular dynamics simulations
by: Turpin, Eleanor R., et al.
Published: (2014)

Molecular dynamics simulation of tau peptides for the investigation of conformational changes induced by specific phosphorylation patterns
by: Gandhi, N., et al.
Published: (2017)

Molecular dynamics simulation of collagen binding to an amyloid-beta monomer and its effect on the peptide structure
by: Zakaria, Norzalina, et al.
Published: (2021)

Identification of a sub-micromolar, non-peptide inhibitor of β-secretase with low neural cytotoxicity through in silico screening
by: Xu, W., et al.
Published: (2010)

Antibody-ligand docking: Insights into peptide-carbohydrate mimicry
by: Yuriev, E., et al.
Published: (2008)

Atomistic molecular dynamics simulations of bioactive engrailed 1 interference peptides (EN1-iPeps)
by: Gandhi, Neha, et al.
Published: (2018)

Molecular analysis of condensation domain in non-ribosomal peptide synthetase (NRPS) gene of Ganoderma boninense
by: Shokrollahi, Neda, et al.
Published: (2018)

Quantitative Seismic Interpretation for Characterizing Carbonate Diagenesis - an Elk/Antelope Gas Field Study
by: Goldberg, A., et al.
Published: (2010)

Deubiquitination of ELK-1 by USP17 regulates its transcriptional potency and cell proliferation
by: Ducker, Charles
Published: (2018)

Evaluation of potential bacterial protease inhibitor properties of selected hydroxyquinoline derivatives : An in silico docking and molecular dynamics simulation approach
by: Riaz, Faiza, et al.
Published: (2023)

Molecular simulations of venom peptide-membrane interactions: Progress and challenges
by: Deplazes, Evelyne
Published: (2018)

The amino-terminal domain of the androgen receptor co-opts extracellular signal-regulated kinase (ERK) docking sites in ELK1 protein to induce sustained gene activation that supports prostate cancer cell growth
by: Rosati, Rayna, et al.
Published: (2016)

In silico simulation of blood glucose-insulin dynamics using MATLAB-Simulink
by: Abdul Malik, Muhammad Iqbal, et al.
Published: (2020)

Computing the two-dimensional infrared spectra of proteins and small peptides using the exciton approach and molecular dynamics simulations
by: Husseini, Fouad
Published: (2017)

Molecular dynamics simulations of CXCL-8 and its interactions with a receptor peptide, heparin fragments and sulfated cyclitols.
by: Gandhi, Neha, et al.
Published: (2011)

Angiotensin converting enzyme (ACE)-peptide interactions: inhibition kinetics, in silico molecular docking and stability study of three novel peptides generated from palm kernel cake proteins
by: Zarei, Mohammad, et al.
Published: (2019)

Identification of potential riboflavin synthase inhibitors by virtual screening and molecular dynamics simulation studies
by: Mohamad Aris, Sayangku Nor Ariati, et al.
Published: (2021)

The development of peptide-based vaccine for leptospirosis: In Silico approach / Salwana Binti Othman
by: Othman, Salwana
Published: (2014)

Identification of natural peptides as a new class of antimalarial drugs by in silico approaches
by: Samy, R., et al.
Published: (2017)

In silico analysis of edible bird’s nest proteins as potential precursors for bioactive peptides
by: Khuzma Din,, et al.
Published: (2022)

In silico determination of physicochemical properties of Lactoferrin peptides isolated from Equine milk
by: Narmuratova, Meiramkul, et al.
Published: (2024)

Peptide Ligands that Interact with Newcastle Disease Virus: Selection, Characterization and Applications
by: Thurai Raja, Priadarishni Ramanujam
Published: (2003)

Molecular dynamics simulations of ligand-induced backbone conformational changes in the binding site of the periplasmic lysine-, arginine-, ornithine-binding protein
by: Yang, A., et al.
Published: (2008)

In silico homology modelling and identification of Tousled-like kinase 1 inhibitors for glioblastoma therapy via high throughput virtual screening protein-ligand docking
by: Kamariah Ibrahim,, et al.
Published: (2018)

Characterisation of Recombinant Aryl Hydrocarbon Receptor Ligand Binding Domain
by: Jiang, Tao
Published: (2004)

Solution structure and in Silico binding of a cyclic peptide with hepatitis B surface antigen
by: Muhamad, Azira, et al.
Published: (2013)

In silico molecular analysis of fructooligosaccaride producing enzymes
by: Nurul Wahida, Abdullah, et al.
Published: (2021)