Cardiac cell modelling: observations from the heart of the cardiac physiome project
In this manuscript we review the state of cardiac cell modelling in the context of international initiatives such as the IUPS Physiome and Virtual Physiological Human Projects, which aim to integrate computational models across scales and physics. In particular we focus on the relationship between e...
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Published: |
Elsevier
2011
|
| Online Access: | https://eprints.nottingham.ac.uk/1757/ |
| _version_ | 1848790669849526272 |
|---|---|
| author | Fink, Martin Niederer, Steven A. Cherry, Elizabeth M. Fenton, Flavio H. Koivumäki, Jussi T. Seemann, Gunnar Thul, Ruediger Zhang, Henggui Sachse, Frank B. Beard, Dan Crampin, Edmund J. Smith, Nicolas P. |
| author_facet | Fink, Martin Niederer, Steven A. Cherry, Elizabeth M. Fenton, Flavio H. Koivumäki, Jussi T. Seemann, Gunnar Thul, Ruediger Zhang, Henggui Sachse, Frank B. Beard, Dan Crampin, Edmund J. Smith, Nicolas P. |
| author_sort | Fink, Martin |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | In this manuscript we review the state of cardiac cell modelling in the context of international initiatives such as the IUPS Physiome and Virtual Physiological Human Projects, which aim to integrate computational models across scales and physics. In particular we focus on the relationship between experimental data and model parameterisation across a range of model types and cellular physiological systems. Finally, in the context of parameter identification and model reuse within the Cardiac Physiome, we suggest some future priority areas for this field. |
| first_indexed | 2025-11-14T18:16:18Z |
| format | Article |
| id | nottingham-1757 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T18:16:18Z |
| publishDate | 2011 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-17572020-05-04T20:23:52Z https://eprints.nottingham.ac.uk/1757/ Cardiac cell modelling: observations from the heart of the cardiac physiome project Fink, Martin Niederer, Steven A. Cherry, Elizabeth M. Fenton, Flavio H. Koivumäki, Jussi T. Seemann, Gunnar Thul, Ruediger Zhang, Henggui Sachse, Frank B. Beard, Dan Crampin, Edmund J. Smith, Nicolas P. In this manuscript we review the state of cardiac cell modelling in the context of international initiatives such as the IUPS Physiome and Virtual Physiological Human Projects, which aim to integrate computational models across scales and physics. In particular we focus on the relationship between experimental data and model parameterisation across a range of model types and cellular physiological systems. Finally, in the context of parameter identification and model reuse within the Cardiac Physiome, we suggest some future priority areas for this field. Elsevier 2011 Article PeerReviewed Fink, Martin, Niederer, Steven A., Cherry, Elizabeth M., Fenton, Flavio H., Koivumäki, Jussi T., Seemann, Gunnar, Thul, Ruediger, Zhang, Henggui, Sachse, Frank B., Beard, Dan, Crampin, Edmund J. and Smith, Nicolas P. (2011) Cardiac cell modelling: observations from the heart of the cardiac physiome project. Progress in Biophysics and Molecular Biology, 104 (1-3). pp. 2-21. ISSN 0079-6107 http://dx.doi.org/10.1016/j.pbiomolbio.2010.03.002 doi:10.1016/j.pbiomolbio.2010.03.002 doi:10.1016/j.pbiomolbio.2010.03.002 |
| spellingShingle | Fink, Martin Niederer, Steven A. Cherry, Elizabeth M. Fenton, Flavio H. Koivumäki, Jussi T. Seemann, Gunnar Thul, Ruediger Zhang, Henggui Sachse, Frank B. Beard, Dan Crampin, Edmund J. Smith, Nicolas P. Cardiac cell modelling: observations from the heart of the cardiac physiome project |
| title | Cardiac cell modelling: observations from the heart of the cardiac physiome project |
| title_full | Cardiac cell modelling: observations from the heart of the cardiac physiome project |
| title_fullStr | Cardiac cell modelling: observations from the heart of the cardiac physiome project |
| title_full_unstemmed | Cardiac cell modelling: observations from the heart of the cardiac physiome project |
| title_short | Cardiac cell modelling: observations from the heart of the cardiac physiome project |
| title_sort | cardiac cell modelling: observations from the heart of the cardiac physiome project |
| url | https://eprints.nottingham.ac.uk/1757/ https://eprints.nottingham.ac.uk/1757/ https://eprints.nottingham.ac.uk/1757/ |