Predicting the response to Ondansetron, a 5HT3 receptor antagonist, in irritable bowel syndrome with diarrhoea: the utility of clinical features and objective biomarkers

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Predicting the response to Ondansetron, a 5HT3 receptor antagonist, in irritable bowel syndrome with diarrhoea: the utility of clinical features and objective biomarkers

Background: Patients with diarrhoea predominant irritable bowel syndrome (IBS-D) suffer from loose frequent stools with associated urgency and fear of incontinence. Relief from these symptoms is an important unmet need. The 5-HT3 receptor antagonist Alosetron has been shown to increase stool consis...

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Bibliographic Details
Main Author:	Garsed, Klara C.
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2014
Subjects:	Drug treatment for irritable bowel syndrome Biomarkers Faecal serine proteases
Online Access:	https://eprints.nottingham.ac.uk/14332/

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