Assessment of DNA-damage repair in breast cancer
Background: Current evidence indicates that DNA damage response (DDR) is a highly complex process that involves various pathways working in an orchestrated and interwoven manner in response to different types of damage to DNA. Although specific defects of DDR remain to be deciphered in cancer as a g...
| Main Author: | Alshareeda, Alaa |
|---|---|
| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2014
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/14250/ |
Similar Items
Clinical and biological significance of RAD51 expression in breast cancer: a key DNA damage response protein
by: Alshareeda, Alaa, et al.
Published: (2016)
by: Alshareeda, Alaa, et al.
Published: (2016)
Targeting DNA damage repair pathways in breast and ovarian cancers
by: Singh, Youvica
Published: (2025)
by: Singh, Youvica
Published: (2025)
Targeting DNA repair and hypoxia to improve radioresponse in breast cancer
by: Aiyappa, Radhika
Published: (2020)
by: Aiyappa, Radhika
Published: (2020)
Assessment of DNA damage and DNA damage response and repair in dormancy-enriched leukemia cells
by: Aldosari, Sahar
Published: (2017)
by: Aldosari, Sahar
Published: (2017)
Evaluation of DNA repair biomarkers in epithelial ovarian and breast cancers
by: Shoqafi, Ahmed
Published: (2025)
by: Shoqafi, Ahmed
Published: (2025)
Pre-clinical development of human apurinic/apyrimidinic endonuclease (APE1) inhibitors for cancer therapy
by: Mohammed, Mohammed Zubair Khuder
Published: (2011)
by: Mohammed, Mohammed Zubair Khuder
Published: (2011)
Targeting ataxia telangiectasia-mutated and Rad3-related kinase (ATR) in PTEN-deficient breast cancers for personalized cancer therapy
by: Alsubhi, Nouf
Published: (2018)
by: Alsubhi, Nouf
Published: (2018)
EXPLORING NOVEL MOLECULAR MECHANISMS OF HELQ IN DNA DAMAGE REPAIR
by: Pan, Jin Ke Michele
Published: (2024)
by: Pan, Jin Ke Michele
Published: (2024)
DNA damage response and anti-apoptotic proteins expression in NPMc+ mutated cells in acute myeloid leukaemia
by: Qutob, Haitham
Published: (2014)
by: Qutob, Haitham
Published: (2014)
Exploring RECQ Helicase landscape in breast cancer
by: Arora, Arvind
Published: (2019)
by: Arora, Arvind
Published: (2019)
Replication of damaged DNA
by: Upton, Amy Louise
Published: (2009)
by: Upton, Amy Louise
Published: (2009)
Investigating a human DNA repair helicase that supports CRISPR editing
by: Cubbon, Andrew
Published: (2022)
by: Cubbon, Andrew
Published: (2022)
Breast cancer prognostic classifiers: combining clinical with molecular profiles
by: Muftah, Abir A. Abdelhadi
Published: (2017)
by: Muftah, Abir A. Abdelhadi
Published: (2017)
Nottingham prognostic index plus (NPI+) predicts risk of distant metastases in primary breast cancer
by: Green, Andrew R., et al.
Published: (2016)
by: Green, Andrew R., et al.
Published: (2016)
Regulation of human heterochromatin protein 1 binding protein 3 (HP1BP3, also known as HP1BP74) in response to the DNA damage
by: Normatova, Makhliyo
Published: (2016)
by: Normatova, Makhliyo
Published: (2016)
Nottingham Prognostic Index Plus: validation of a clinical decision making tool in breast cancer in an independent series
by: Green, Andrew R., et al.
Published: (2016)
by: Green, Andrew R., et al.
Published: (2016)
DNA repair in the archaea – an emerging picture
by: White, Malcolm F., et al.
Published: (2018)
by: White, Malcolm F., et al.
Published: (2018)
Exploring the role of cell signalling and DNA damage pathways in primary surgically resected ovarian cancer
by: Alabdullah, Mussalam Layth
Published: (2021)
by: Alabdullah, Mussalam Layth
Published: (2021)
Structural and genetic analyses of the RdgC protein in Escherichia coli
by: Yu, Jing
Published: (2009)
by: Yu, Jing
Published: (2009)
Interactions of the Bacillus subtilis DnaE polymerase with replisomal proteins modulate its activity and fidelity
by: Paschalis, Vasileios, et al.
Published: (2017)
by: Paschalis, Vasileios, et al.
Published: (2017)
Alternative DNA Repair During Meiosis in the Budding Yeast S.
cerevisiae
by: Reeves, Ryan Peter
Published: (2025)
by: Reeves, Ryan Peter
Published: (2025)
Targeting DNA repair for personalisation of glioblastoma therapy
by: Perry, Christina Joy
Published: (2016)
by: Perry, Christina Joy
Published: (2016)
Combatting chemoresistance: an analysis of DNA repair proteins ERCC1 and XPF and their chemotherapeutic implications in ovarian cancer
by: Griffin, Michaela
Published: (2019)
by: Griffin, Michaela
Published: (2019)
Integration of rank-partition and sequential wrapper techniques for feature selection of breast cancer microarray data
by: Abdulwahhab, Ahmed Abbas
Published: (2015)
by: Abdulwahhab, Ahmed Abbas
Published: (2015)
Evaluation of Replication Protein A (RPA) as a prognostic and therapeutic target in breast and ovarian cancer
by: Algethami, Mashael
Published: (2024)
by: Algethami, Mashael
Published: (2024)
The biological heterogeneity of oestrogen receptor positive breast cancer and its phenotypic characterisation
by: Habashy, Hany Onsy Fouad Ibrahim
Published: (2011)
by: Habashy, Hany Onsy Fouad Ibrahim
Published: (2011)
Treatment-focused DNA testing for newly diagnosed breast cancer patients: some implications for clinical practice
by: Lobb, Elizabeth, et al.
Published: (2010)
by: Lobb, Elizabeth, et al.
Published: (2010)
Genome architecture and DNA replication in Haloferax volcanii
by: Marriott, Hannah
Published: (2018)
by: Marriott, Hannah
Published: (2018)
Computational pathology and deciphering the complexity of HER2 expression in breast cancer
by: Atallah, Nehal Mohammed
Published: (2025)
by: Atallah, Nehal Mohammed
Published: (2025)
Biological assessment - developing a novel tool to guide treatment decision in older women with primary breast cancer
by: Parks, Ruth M.
Published: (2023)
by: Parks, Ruth M.
Published: (2023)
Association between hypermethylation of DNA repetitive elements in white blood cell DNA and pancreatic cancer
by: Neale, R., et al.
Published: (2014)
by: Neale, R., et al.
Published: (2014)
Genetic and biochemical analysis of the Hel308 Helicase in the Archaeon Haloferax volcanii
by: Lever, Rebecca
Published: (2020)
by: Lever, Rebecca
Published: (2020)
Biochemical and genetic analysis of Lhr, a mysterious helicase/glycosylase conserved across species
by: Buckley, Ryan J.
Published: (2023)
by: Buckley, Ryan J.
Published: (2023)
RECQ1 expression is upregulated in response to DNA damage and in a p53-dependent manner
by: Parvathaneni, Swetha, et al.
Published: (2017)
by: Parvathaneni, Swetha, et al.
Published: (2017)
Analysis of catalytic and non-catalytic regions of the human DNA repair helicase HelQ
by: Jenkins, T
Published: (2021)
by: Jenkins, T
Published: (2021)
Serum autoantibodies as tumour markers in breast cancer: their role in screening, diagnosis and prognosis
by: Khan, Hamed N.
Published: (2009)
by: Khan, Hamed N.
Published: (2009)
Synthesis, characterization and DNA binding activity of a potential DNA intercalator
by: Harun, Siti Norain, et al.
Published: (2016)
by: Harun, Siti Norain, et al.
Published: (2016)
Design and synthesis of new 1-alkyl-3-butylimidazolium bromide ionic liquids as media for DNA solvation
by: Jumbri, Khairulazhar
Published: (2015)
by: Jumbri, Khairulazhar
Published: (2015)
Development of a clinically relevant subclassification of luminal breast cancer related to response to endocrine therapy
by: Alfarsi, Lutfi
Published: (2020)
by: Alfarsi, Lutfi
Published: (2020)
The repair of DNA breaks in Escherichia coli and analysis of the bacterial recombination protein RecN
by: Wood, Stuart Robert
Published: (2009)
by: Wood, Stuart Robert
Published: (2009)
Similar Items
-
Clinical and biological significance of RAD51 expression in breast cancer: a key DNA damage response protein
by: Alshareeda, Alaa, et al.
Published: (2016) -
Targeting DNA damage repair pathways in breast and ovarian cancers
by: Singh, Youvica
Published: (2025) -
Targeting DNA repair and hypoxia to improve radioresponse in breast cancer
by: Aiyappa, Radhika
Published: (2020) -
Assessment of DNA damage and DNA damage response and repair in dormancy-enriched leukemia cells
by: Aldosari, Sahar
Published: (2017) -
Evaluation of DNA repair biomarkers in epithelial ovarian and breast cancers
by: Shoqafi, Ahmed
Published: (2025)