Development of a detection system towards a basophil-microarray for the diagnosis of allergies

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Development of a detection system towards a basophil-microarray for the diagnosis of allergies

Allergic responses are mainly mediated by immunoglobulin E (IgE) and mast cells or basophils expressing the high-affinity IgE receptor FcεRI. Cross-linking of FcεRI and IgE complexes with allergen induces basophil degranulation and release of inflammatory chemical mediators, leading to clinical sym...

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Bibliographic Details
Main Author:	Wang, Xiaowei
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2014
Online Access:	https://eprints.nottingham.ac.uk/14187/

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