Synthesis of nanomaterials for biomedical applications

The field of nanotechnology is growing vastly, both as a field of research and in commercial applications. This rapid growth calls for synthesis methods which can produce high quality nanomaterials, while being scalable. This thesis describes an investigation into the use of a continuous hydrothe...

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Main Author: Tang, Selina Vi Yu
Format: Thesis (University of Nottingham only)
Language:English
Published: 2014
Online Access:https://eprints.nottingham.ac.uk/14101/
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author Tang, Selina Vi Yu
author_facet Tang, Selina Vi Yu
author_sort Tang, Selina Vi Yu
building Nottingham Research Data Repository
collection Online Access
description The field of nanotechnology is growing vastly, both as a field of research and in commercial applications. This rapid growth calls for synthesis methods which can produce high quality nanomaterials, while being scalable. This thesis describes an investigation into the use of a continuous hydrothermal reactor for the synthesis of nanomaterials, with potential use in three different biomedical applications – bone scaffolds, fluorescent biomarkers, and MRI contrast agents. The first chapter of this thesis provides an overview of nanotechnology: the advantages of nanoscale, the commercial industries which can benefit, and the predominant methods currently used to produce nanomaterials. Some advantages and drawbacks of each synthesis route are given, concluding with a description of the Nozzle reactor – the patented technology used for nanomaterial synthesis in this Thesis. Chapter 2 then focusses on the characterisation techniques used in this thesis, detailing the principles of how data is obtained, as well as highlighting the limitations of each method. With the background information in place, chapters 3, 4 and 5 describe more specific nanomaterials and how they can be applied to each of the aforementioned biomedical fields. These chapters provide the technical details of how various nanomaterials can be synthesised using the Nozzle reactor, and the structural data (crystallinity, particle size) obtained from these samples. Furthermore, the functional properties of these nanomaterials are tested and the results, along with a discussion of any trends, are presented. Finally, this thesis concludes with a summary of the results described and emphasises the key areas where further work can be conducted.
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spelling nottingham-141012025-02-28T11:28:51Z https://eprints.nottingham.ac.uk/14101/ Synthesis of nanomaterials for biomedical applications Tang, Selina Vi Yu The field of nanotechnology is growing vastly, both as a field of research and in commercial applications. This rapid growth calls for synthesis methods which can produce high quality nanomaterials, while being scalable. This thesis describes an investigation into the use of a continuous hydrothermal reactor for the synthesis of nanomaterials, with potential use in three different biomedical applications – bone scaffolds, fluorescent biomarkers, and MRI contrast agents. The first chapter of this thesis provides an overview of nanotechnology: the advantages of nanoscale, the commercial industries which can benefit, and the predominant methods currently used to produce nanomaterials. Some advantages and drawbacks of each synthesis route are given, concluding with a description of the Nozzle reactor – the patented technology used for nanomaterial synthesis in this Thesis. Chapter 2 then focusses on the characterisation techniques used in this thesis, detailing the principles of how data is obtained, as well as highlighting the limitations of each method. With the background information in place, chapters 3, 4 and 5 describe more specific nanomaterials and how they can be applied to each of the aforementioned biomedical fields. These chapters provide the technical details of how various nanomaterials can be synthesised using the Nozzle reactor, and the structural data (crystallinity, particle size) obtained from these samples. Furthermore, the functional properties of these nanomaterials are tested and the results, along with a discussion of any trends, are presented. Finally, this thesis concludes with a summary of the results described and emphasises the key areas where further work can be conducted. 2014-07-09 Thesis (University of Nottingham only) NonPeerReviewed application/pdf en arr https://eprints.nottingham.ac.uk/14101/1/Synthesis_of_Nanomaterials_for_Biomedical_Applications_by_Selina_Vi_Yu_Tang_%28eTheses%29.pdf Tang, Selina Vi Yu (2014) Synthesis of nanomaterials for biomedical applications. PhD thesis, University of Nottingham.
spellingShingle Tang, Selina Vi Yu
Synthesis of nanomaterials for biomedical applications
title Synthesis of nanomaterials for biomedical applications
title_full Synthesis of nanomaterials for biomedical applications
title_fullStr Synthesis of nanomaterials for biomedical applications
title_full_unstemmed Synthesis of nanomaterials for biomedical applications
title_short Synthesis of nanomaterials for biomedical applications
title_sort synthesis of nanomaterials for biomedical applications
url https://eprints.nottingham.ac.uk/14101/