Human beta-defensin gene copy number variation and consequences in disease and evolution

QR Code

Human beta-defensin gene copy number variation and consequences in disease and evolution

Research on human genetic variation has shown that the human genome is not a fixed, invariant framework, but that there can be extensive structural variation. This variation includes copy number variation (CNV), which can lead to changes in DNA dosage contributing significantly to variation between...

Full description

Bibliographic Details
Main Author:	Pala, Raquel Rodrigues
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2012
Online Access:	https://eprints.nottingham.ac.uk/14020/

Similar Items

Measurement methods and accuracy in copy number variation: failure to replicate associations of beta-defensin copy number with Crohn's disease.
by: Aldhous, Marian C., et al.
Published: (2010)

Generation of diversity at the human beta-defensin copy number
by: Abu Bakar, Suhaili
Published: (2010)

Characterization of the alpha defensin copy number variation in humans
by: Khan, Fayeza Fatima
Published: (2012)

Descriptive study on the origin and evolution of beta- defensins copy number variable gene using multigenerational family pedigrees
by: Musa, Nurul Azmah
Published: (2019)

Quantification of beta-defensin copy number variable genes in relation to inflammation in diabetic patients
by: Yusoff, Maryam Jamielah
Published: (2015)

Copy number variation of the beta-defensin genes in Europeans: no supporting evidence for association with lung function, chronic obstructive pulmonary disease or asthma
by: Ahuja, Sunil K., et al.
Published: (2014)

Quantification of beta-defensins (DEFB) gene copy number variations in relation to inflammation in type 2 diabetes mellitus and diabetic nephropathy patients
by: Yusoff, Maryam Jamielah, et al.
Published: (2020)

Accurate measurement of gene copy number for human alpha-defensin DEFA1A3
by: Khan, Fayeza F., et al.
Published: (2013)

A Preliminary Study On The Distribution Of Beta Defensins Copy Number Variable Gene In Different Ethnics Of Sarawak, Malaysian Borneo
by: Zahirunisa, Abd Rahim, et al.
Published: (2017)

A preliminary study on the distribution of beta defensins copy number variable gene in different ethnics of Sarawak, Malaysian Borneo
by: Abd Rahim, Zahirunisa, et al.
Published: (2017)

Association of beta-defensin gene copy number variation with CD4 count and viral load among Malaysian ethnics hiv patients after HAART initiation
by: Achim, Nurfarahin Hanini
Published: (2020)

Low alpha-defensin gene copy number increases the risk for IgA nephropathy and renal dysfunction
by: Ai, Zhen, et al.
Published: (2016)

Measuring human salivary amylase copy number variation
by: Dhar, Sugandha
Published: (2010)

Expression of beta defensin genes in frozen thawed and cultured immortalised human corneal epithelial cell line
by: Azmi, Nurul Shakirah, et al.
Published: (2018)

Host defence peptide (HDP) human beta defensin 9 (HBD9)
by: Omar, Nazri
Published: (2016)

Copy number variation of human AMY1 is a minor contributor to variation in salivary amylase expression and activity
by: Carpenter, Danielle, et al.
Published: (2017)

Allelic structures and mechanisms of copy number change at the human DEFA1A3 copy number variable locus
by: Black, Holly Ann
Published: (2014)

A quantitative PCR approach to determine gene copy number
by: Solomon, P., et al.
Published: (2008)

Copy Number Variation Analysis of 100 Twin Pairs Enriched for Neurodevelopmental Disorders
by: Stamouli, S., et al.
Published: (2018)

Copy number variation of FCGR3B gene among severe dengue patient in Malaysia / Umi Shakina Haridan
by: Haridan, Umi Shakina
Published: (2015)

Association of copy number variations in complement factor H-related genes among age-related macular degenerative subjects
by: Md Bakri, Norshakimah, et al.
Published: (2017)

Copy number variations in Friesian horses and genetic risk factors for insect bite hypersensitivity
by: Schurink, Anouk, et al.
Published: (2018)

Copy number variations of Orang Asli’ (Negrito) from Peninsular Malaysia / Siti Shuhada Mokhtar
by: Mokhtar, Siti Shuhada
Published: (2015)

Analysis of alpha defensin variation in samples from periodontitis patients
by: Moise, Eric Constantin
Published: (2018)

Relative quantification of human B-defensins gene expression in pterygium and normal conjunctiva samples
by: Abubakar, Sa'adatu Aliyu, et al.
Published: (2020)

Correlation between HPV infection and human beta-defensin mRNA expression in pterygium and normal conjunctiva epithelial cells
by: Aliyu, Abubakar Saadatu
Published: (2017)

The role of single nucleotide polymorphisms and copy number variations in the spectrum of non-alcoholic fatty liver disease / Shamsul bin Mohd Zain
by: Mohd Zain, Shamsul
Published: (2013)

Human alpha defensin CNV haplotype diversity
by: Xu, Xiao
Published: (2018)

The identification of copy number variation of CNV esv27061 among young adults with hypertension: preliminary findings
by: Shaik Alaudeen, Siti Radziah, et al.
Published: (2017)

Copy number variation of CCL3L1 among three major ethnic groups in Malaysia
by: Jamaluddin, Jalilah, et al.
Published: (2020)

Investigating the functional properties of the multi-allelic copy number variable DEFA1A3 locus and their effects on gene expression and disease
by: AlHamidi, Reem
Published: (2023)

Analysis of genetic factors influencing alpha-defensin gene expression
by: Necsoiu, Paula Eugenia
Published: (2018)

Identification and characterization of copy number variations (CNVs) in dengue patients and its impact with vascular leakage / Zuraihan Zakaria
by: Zakaria, Zuraihan
Published: (2016)

Identification and characterization of copy number variations (CNVs) in dengue patients and its impact with vascular leakage / Zuraihan Zakaria
by: Zakaria, Zuraihan
Published: (2016)

Effects of copy number variable regions on local gene expression in white blood cells of Mexican Americans
by: Blackburn, A., et al.
Published: (2015)

TP53 copy number expansion is associated with the evolution of increased body size and an enhanced DNA damage response in elephants.
by: Sulak, Michael, et al.
Published: (2016)

TP53 copy number expansion is associated with the evolution of increased body size and an enhanced DNA damage response in elephants
by: Sulak, Michael, et al.
Published: (2016)

Obesity, starch digestion and amylase: association between copy number variants at human salivary (AMY1) and pancreatic (AMY2) amylase genes
by: Carpenter, Danielle, et al.
Published: (2015)

Production of novel antimicrobial peptide human beta defensin 9 and its efficacy against common eye pathogenic bacteria in different salt concentration
by: Ab Hamid, Nurul Atikah
Published: (2018)

CCL3L1 copy number and susceptibility to malaria
by: Carpenter, Danielle, et al.
Published: (2012)