Asymmetric piperidine synthesis

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Asymmetric piperidine synthesis

It has been demonstrated that bakers' yeast reduction of 1-tert-butyl-2-methyl 3-oxo-piperidine-1,2-dicarboxylate gives (2R, 3S), 1-tert-butyl-2-methyl 3-hydroxy-piperidine-1,2-dicarboxylate in 80% chemical yield with >99% d.e. and >97% e.e. Also bakers' yeast reduction of 1-tert-but...

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Bibliographic Details
Main Author:	Lewis, Neil
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	1995
Online Access:	https://eprints.nottingham.ac.uk/13293/

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