Investigation of Taxol biosynthetic genes for the production of novel taxanes in heterologous plant systems

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Investigation of Taxol biosynthetic genes for the production of novel taxanes in heterologous plant systems

The diterpenoid paclitaxel (TaxolTM) is one of the most effective anticancer drugs, used against a wide range of cancers. It is produced as a secondary metabolite in the vascular cambial region of the bark of Taxus brevifolia from which it was first extracted in 1971. Taxol also accumulates in low c...

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Bibliographic Details
Main Author:	Narraidoo, Nathalie
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2011
Online Access:	https://eprints.nottingham.ac.uk/13269/

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