Spatial distortion in MRI with application to stereotactic neurosurgery

The aim of this work was to implement a thorough method for quantifying the errors introduced to frame-based neurosurgical stereotactic procedures by the use of MRI. Chang & Fitzpatrick's reversed gradient distortion correction method was used, in combination with a phantom, to measure thes...

Full description

Bibliographic Details
Main Author: Morgan, Paul Simon
Format: Thesis (University of Nottingham only)
Language:English
Published: 1999
Online Access:https://eprints.nottingham.ac.uk/13091/
_version_ 1848791649440759808
author Morgan, Paul Simon
author_facet Morgan, Paul Simon
author_sort Morgan, Paul Simon
building Nottingham Research Data Repository
collection Online Access
description The aim of this work was to implement a thorough method for quantifying the errors introduced to frame-based neurosurgical stereotactic procedures by the use of MRI. Chang & Fitzpatrick's reversed gradient distortion correction method was used, in combination with a phantom, to measure these errors. Spatial distortion in MR images of between 1 mm and 2 mm was measured. Further analysis showed that this typically introduced an additional error in the coordinate of the actual treatment point of 0.7 mm. The implications of this are discussed. The main source of distortion in the MR images used for stereotaxis was found to be the head ring. A comparison between imaging sequences and MR scanners revealed that the spatial distortion depends mainly on the bandwidth per pixel of the sequence rather than other differences in the imaging sequences. By comparison with a phase map distortion correction technique, the imaging parameters required to allow successful distortion correction with the reversed gradient method were identified. The most important was the use of full Fourier spin echo acquisitions. The reversed gradient correction method was applied to two contemporary EPI techniques. Considerable improvement was seen in the production of ADC maps after the images had been corrected for distortion. The method also was shown to be valid in application to BOLD fMRI data.
first_indexed 2025-11-14T18:31:52Z
format Thesis (University of Nottingham only)
id nottingham-13091
institution University of Nottingham Malaysia Campus
institution_category Local University
language English
last_indexed 2025-11-14T18:31:52Z
publishDate 1999
recordtype eprints
repository_type Digital Repository
spelling nottingham-130912025-02-28T11:23:06Z https://eprints.nottingham.ac.uk/13091/ Spatial distortion in MRI with application to stereotactic neurosurgery Morgan, Paul Simon The aim of this work was to implement a thorough method for quantifying the errors introduced to frame-based neurosurgical stereotactic procedures by the use of MRI. Chang & Fitzpatrick's reversed gradient distortion correction method was used, in combination with a phantom, to measure these errors. Spatial distortion in MR images of between 1 mm and 2 mm was measured. Further analysis showed that this typically introduced an additional error in the coordinate of the actual treatment point of 0.7 mm. The implications of this are discussed. The main source of distortion in the MR images used for stereotaxis was found to be the head ring. A comparison between imaging sequences and MR scanners revealed that the spatial distortion depends mainly on the bandwidth per pixel of the sequence rather than other differences in the imaging sequences. By comparison with a phase map distortion correction technique, the imaging parameters required to allow successful distortion correction with the reversed gradient method were identified. The most important was the use of full Fourier spin echo acquisitions. The reversed gradient correction method was applied to two contemporary EPI techniques. Considerable improvement was seen in the production of ADC maps after the images had been corrected for distortion. The method also was shown to be valid in application to BOLD fMRI data. 1999 Thesis (University of Nottingham only) NonPeerReviewed application/pdf en arr https://eprints.nottingham.ac.uk/13091/1/299705.pdf Morgan, Paul Simon (1999) Spatial distortion in MRI with application to stereotactic neurosurgery. PhD thesis, University of Nottingham.
spellingShingle Morgan, Paul Simon
Spatial distortion in MRI with application to stereotactic neurosurgery
title Spatial distortion in MRI with application to stereotactic neurosurgery
title_full Spatial distortion in MRI with application to stereotactic neurosurgery
title_fullStr Spatial distortion in MRI with application to stereotactic neurosurgery
title_full_unstemmed Spatial distortion in MRI with application to stereotactic neurosurgery
title_short Spatial distortion in MRI with application to stereotactic neurosurgery
title_sort spatial distortion in mri with application to stereotactic neurosurgery
url https://eprints.nottingham.ac.uk/13091/