Threshold behaviour and final outcome of an epidemic on a random network with household structure

This paper considers a stochastic SIR (susceptible-infective-removed) epidemic model in which individuals may make infectious contacts in two ways, both within 'households' (which for ease of exposition are assumed to have equal size) and along the edges of a random graph describing additi...

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Main Authors: Ball, Frank G., Sirl, David J., Trapman, Pieter
Format: Article
Published: Applied Probability Trust 2009
Subjects:
Online Access:https://eprints.nottingham.ac.uk/1299/
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author Ball, Frank G.
Sirl, David J.
Trapman, Pieter
author_facet Ball, Frank G.
Sirl, David J.
Trapman, Pieter
author_sort Ball, Frank G.
building Nottingham Research Data Repository
collection Online Access
description This paper considers a stochastic SIR (susceptible-infective-removed) epidemic model in which individuals may make infectious contacts in two ways, both within 'households' (which for ease of exposition are assumed to have equal size) and along the edges of a random graph describing additional social contacts. Heuristically-motivated branching process approximations are described, which lead to a threshold parameter for the model and methods for calculating the probability of a major outbreak, given few initial infectives, and the expected proportion of the population who are ultimately infected by such a major outbreak. These approximate results are shown to be exact as the number of households tends to infinity by proving associated limit theorems. Moreover, simulation studies indicate that these asymptotic results provide good approximations for modestly-sized finite populations. The extension to unequal sized households is discussed briefly.
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spelling nottingham-12992020-05-04T20:26:35Z https://eprints.nottingham.ac.uk/1299/ Threshold behaviour and final outcome of an epidemic on a random network with household structure Ball, Frank G. Sirl, David J. Trapman, Pieter This paper considers a stochastic SIR (susceptible-infective-removed) epidemic model in which individuals may make infectious contacts in two ways, both within 'households' (which for ease of exposition are assumed to have equal size) and along the edges of a random graph describing additional social contacts. Heuristically-motivated branching process approximations are described, which lead to a threshold parameter for the model and methods for calculating the probability of a major outbreak, given few initial infectives, and the expected proportion of the population who are ultimately infected by such a major outbreak. These approximate results are shown to be exact as the number of households tends to infinity by proving associated limit theorems. Moreover, simulation studies indicate that these asymptotic results provide good approximations for modestly-sized finite populations. The extension to unequal sized households is discussed briefly. Applied Probability Trust 2009 Article PeerReviewed Ball, Frank G., Sirl, David J. and Trapman, Pieter (2009) Threshold behaviour and final outcome of an epidemic on a random network with household structure. Advances in Applied Probability, 41 (3). pp. 765-796. Branching process; coupling; epidemic process; final outcome; households; local and global contacts; random graph; susceptibility set; threshold theorem http://www.appliedprobability.org/content.aspx?Group=journals&Page=apjournals
spellingShingle Branching process; coupling; epidemic process; final outcome; households; local and global contacts; random graph; susceptibility set; threshold theorem
Ball, Frank G.
Sirl, David J.
Trapman, Pieter
Threshold behaviour and final outcome of an epidemic on a random network with household structure
title Threshold behaviour and final outcome of an epidemic on a random network with household structure
title_full Threshold behaviour and final outcome of an epidemic on a random network with household structure
title_fullStr Threshold behaviour and final outcome of an epidemic on a random network with household structure
title_full_unstemmed Threshold behaviour and final outcome of an epidemic on a random network with household structure
title_short Threshold behaviour and final outcome of an epidemic on a random network with household structure
title_sort threshold behaviour and final outcome of an epidemic on a random network with household structure
topic Branching process; coupling; epidemic process; final outcome; households; local and global contacts; random graph; susceptibility set; threshold theorem
url https://eprints.nottingham.ac.uk/1299/
https://eprints.nottingham.ac.uk/1299/