Potency and species specificity of aryl hydrocarbon receptor ligands

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Potency and species specificity of aryl hydrocarbon receptor ligands

The aryl hydrocarbon receptor (AhR) binds a wide range of structurally diverse compounds such as halogenated dibenzo-p-dioxins, dibenzofurans and biphenyls which are abundant in the environment. Activation of AhR leads to the regulation of a battery of xenobiotic enzymes including cytochrome P4501A1...

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Bibliographic Details
Main Author:	Wall, Richard John
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2012
Subjects:	AhR Aryl Hydrocarbon receptor TCDD mouse human rat species differences concentration response curve cell culture RNA qRT-PCR real time PCR ligand binding
Online Access:	https://eprints.nottingham.ac.uk/12798/

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