Activity of the aurora kinase B inhibitor AZD1152 in acute myeloid leukaemia

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Activity of the aurora kinase B inhibitor AZD1152 in acute myeloid leukaemia

Aurora kinases play an essential role in orchestrating chromosome alignment, segregation and cytokinesis during mitotic progression, with both aurora-A and B frequently over-expressed in a variety of human malignancies including those of leukaemic origin. Acute myeloid leukaemia (AML) is a heterogen...

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Bibliographic Details
Main Author:	Grundy, Martin
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2012
Online Access:	https://eprints.nottingham.ac.uk/12758/

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