Understanding the role of eIF4A in gene regulation in health and disease

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Understanding the role of eIF4A in gene regulation in health and disease

Eukaryotic initiation factor 4A (eIF4A) is an ATP-dependent RNA helicase responsible for unwinding the secondary structure of mRNAs. In humans, eIF4A exists as three separate paralogs: eIF4AI and eIF4AII possess a high degree of homology while eIF4AIII is distinct. Knockdown of eIF4AII had no effect...

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Bibliographic Details
Main Author:	Webb, Thomas E.
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2012
Subjects:	eIF4A EGFR Alzheimer's Cancer
Online Access:	https://eprints.nottingham.ac.uk/12724/

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