Angiogenesis in the pathogenesis of inflammatory joint and lung diseases
This paper reviews hypotheses about roles of angiogenesis in the pathogenesis of inflammatory disease in two organs, the synovial joint and the lung. Neovascularisation is a fundamental process for growth and tissue repair after injury. Nevertheless, it may contribute to a variety of chronic inflamm...
| Main Authors: | , |
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| Format: | Article |
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BioMEd Central
2001
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| Online Access: | https://eprints.nottingham.ac.uk/126/ |
| _version_ | 1848790346881826816 |
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| author | Walsh, D.A. Pearson, C.I. |
| author_facet | Walsh, D.A. Pearson, C.I. |
| author_sort | Walsh, D.A. |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | This paper reviews hypotheses about roles of angiogenesis in the pathogenesis of inflammatory disease in two organs, the synovial joint and the lung. Neovascularisation is a fundamental process for growth and tissue repair after injury. Nevertheless, it may contribute to a variety of chronic inflammatory diseases, including rheumatoid arthritis, osteoarthritis, asthma, and pulmonary fibrosis. Inflammation can promote angiogenesis, and new vessels may enhance tissue inflammation. Angiogenesis in inflammatory disease may also contribute to tissue growth, disordered tissue perfusion, abnormal ossification, and enhanced responses to normal or pathological stimuli. Angiogenesis inhibitors may reduce inflammation and may also help to restore appropriate tissue structure and function |
| first_indexed | 2025-11-14T18:11:10Z |
| format | Article |
| id | nottingham-126 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T18:11:10Z |
| publishDate | 2001 |
| publisher | BioMEd Central |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-1262020-05-04T20:32:49Z https://eprints.nottingham.ac.uk/126/ Angiogenesis in the pathogenesis of inflammatory joint and lung diseases Walsh, D.A. Pearson, C.I. This paper reviews hypotheses about roles of angiogenesis in the pathogenesis of inflammatory disease in two organs, the synovial joint and the lung. Neovascularisation is a fundamental process for growth and tissue repair after injury. Nevertheless, it may contribute to a variety of chronic inflammatory diseases, including rheumatoid arthritis, osteoarthritis, asthma, and pulmonary fibrosis. Inflammation can promote angiogenesis, and new vessels may enhance tissue inflammation. Angiogenesis in inflammatory disease may also contribute to tissue growth, disordered tissue perfusion, abnormal ossification, and enhanced responses to normal or pathological stimuli. Angiogenesis inhibitors may reduce inflammation and may also help to restore appropriate tissue structure and function BioMEd Central 2001 Article PeerReviewed Walsh, D.A. and Pearson, C.I. (2001) Angiogenesis in the pathogenesis of inflammatory joint and lung diseases. Arthritis Research, 3 (3). pp. 147-153. |
| spellingShingle | Walsh, D.A. Pearson, C.I. Angiogenesis in the pathogenesis of inflammatory joint and lung diseases |
| title | Angiogenesis in the pathogenesis of inflammatory joint and lung diseases |
| title_full | Angiogenesis in the pathogenesis of inflammatory joint and lung diseases |
| title_fullStr | Angiogenesis in the pathogenesis of inflammatory joint and lung diseases |
| title_full_unstemmed | Angiogenesis in the pathogenesis of inflammatory joint and lung diseases |
| title_short | Angiogenesis in the pathogenesis of inflammatory joint and lung diseases |
| title_sort | angiogenesis in the pathogenesis of inflammatory joint and lung diseases |
| url | https://eprints.nottingham.ac.uk/126/ |