Pathological validation and significance of micrometastasis in sentinel nodes in primary breast cancer
In embracing a multidisciplinary approach to the management of patients with sentinel node biopsy in breast cancer, the pathologist task is to screen sentinel nodes for possible metastasis. The consequences of missing sentinel node micrometastasis can directly influence treatment strategies, and thi...
| Main Authors: | , , , , |
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| Format: | Article |
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BioMed Central Ltd
2001
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| Online Access: | https://eprints.nottingham.ac.uk/125/ |
| _version_ | 1848790346608148480 |
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| author | Rampaul, R.S. Miremadi, A. Pinder, S.E. Lee, A. Ellis, I.O. |
| author_facet | Rampaul, R.S. Miremadi, A. Pinder, S.E. Lee, A. Ellis, I.O. |
| author_sort | Rampaul, R.S. |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | In embracing a multidisciplinary approach to the management of patients with sentinel node biopsy in breast cancer, the pathologist task is to screen sentinel nodes for possible metastasis. The consequences of missing sentinel node micrometastasis can directly influence treatment strategies, and this screening therefore has to be performed with more attention than usual. There is presently great diversity in the histopathological work-up of sentinel nodes, with many centres employing additional techniques such as immunohistochemistry, reverse transcription polymerase chain reaction or flow cytometry in addition to routine haematoxylin and eosin staining. In this review, we address the pathological validation and significance of micrometastasis in sentinel node biopsy in primary breast cancer |
| first_indexed | 2025-11-14T18:11:09Z |
| format | Article |
| id | nottingham-125 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T18:11:09Z |
| publishDate | 2001 |
| publisher | BioMed Central Ltd |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-1252020-05-04T20:32:47Z https://eprints.nottingham.ac.uk/125/ Pathological validation and significance of micrometastasis in sentinel nodes in primary breast cancer Rampaul, R.S. Miremadi, A. Pinder, S.E. Lee, A. Ellis, I.O. In embracing a multidisciplinary approach to the management of patients with sentinel node biopsy in breast cancer, the pathologist task is to screen sentinel nodes for possible metastasis. The consequences of missing sentinel node micrometastasis can directly influence treatment strategies, and this screening therefore has to be performed with more attention than usual. There is presently great diversity in the histopathological work-up of sentinel nodes, with many centres employing additional techniques such as immunohistochemistry, reverse transcription polymerase chain reaction or flow cytometry in addition to routine haematoxylin and eosin staining. In this review, we address the pathological validation and significance of micrometastasis in sentinel node biopsy in primary breast cancer BioMed Central Ltd 2001 Article PeerReviewed Rampaul, R.S., Miremadi, A., Pinder, S.E., Lee, A. and Ellis, I.O. (2001) Pathological validation and significance of micrometastasis in sentinel nodes in primary breast cancer. Breast Cancer Research, 3 (2). pp. 113-116. |
| spellingShingle | Rampaul, R.S. Miremadi, A. Pinder, S.E. Lee, A. Ellis, I.O. Pathological validation and significance of micrometastasis in sentinel nodes in primary breast cancer |
| title | Pathological validation and significance of micrometastasis in sentinel nodes in primary breast cancer |
| title_full | Pathological validation and significance of micrometastasis in sentinel nodes in primary breast cancer |
| title_fullStr | Pathological validation and significance of micrometastasis in sentinel nodes in primary breast cancer |
| title_full_unstemmed | Pathological validation and significance of micrometastasis in sentinel nodes in primary breast cancer |
| title_short | Pathological validation and significance of micrometastasis in sentinel nodes in primary breast cancer |
| title_sort | pathological validation and significance of micrometastasis in sentinel nodes in primary breast cancer |
| url | https://eprints.nottingham.ac.uk/125/ |