Spectroscopic analysis of scattering media via different quantification techniques

This thesis outlines problems in the estimation of concentration value of an absorber present in a medium that is scattering and shortcomings of using the currently available techniques for the characterisation of such a scattering medium. The work describes experiment and analytic techniques used t...

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Main Author: Huong, Audrey Kah Ching
Format: Thesis (University of Nottingham only)
Language:English
Published: 2012
Subjects:
Online Access:https://eprints.nottingham.ac.uk/12464/
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author Huong, Audrey Kah Ching
author_facet Huong, Audrey Kah Ching
author_sort Huong, Audrey Kah Ching
building Nottingham Research Data Repository
collection Online Access
description This thesis outlines problems in the estimation of concentration value of an absorber present in a medium that is scattering and shortcomings of using the currently available techniques for the characterisation of such a scattering medium. The work describes experiment and analytic techniques used to overcome these problems. This thesis explored experimentally the practicality of using polarisation subtraction technique to minimise the effects of scattering components on the measured data. This work also considered the case when this technique has not been used owing to its limited application, and to that end, the improved linear equation and nonlinear fitting models, and gradient processing method were developed on the basis of the assumed behaviour of how a medium’s scattering coefficient changes with wavelength to provide information about the fractional concentration value of an absorber. The performance of these techniques evaluated via simulation showed that linear equation model has the fastest processing speed, nonlinear fitting method is robust to system noise and is able to provide an overall more accurate estimate of value with mean of errors of less than ±1%. The gradient processing method has intermediate performances with accuracy of its estimated value improved by about 30% with an increase in the spectral resolution from 1 nm to 0.5 nm. This work concludes that gradient processing method would be employed if accuracy of estimated value, noise robustness and computing time are of concern. However, nonlinear fitting method would be chosen in case high accuracy of the estimated value is required. Both of these methods can be suitably used as complementary techniques to clinical assessment of skin grafts and burnt skin. The simultaneous solution of linear equation model works well if all the measurement parameters are known.
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format Thesis (University of Nottingham only)
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institution University of Nottingham Malaysia Campus
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language English
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publishDate 2012
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spelling nottingham-124642025-02-28T11:19:27Z https://eprints.nottingham.ac.uk/12464/ Spectroscopic analysis of scattering media via different quantification techniques Huong, Audrey Kah Ching This thesis outlines problems in the estimation of concentration value of an absorber present in a medium that is scattering and shortcomings of using the currently available techniques for the characterisation of such a scattering medium. The work describes experiment and analytic techniques used to overcome these problems. This thesis explored experimentally the practicality of using polarisation subtraction technique to minimise the effects of scattering components on the measured data. This work also considered the case when this technique has not been used owing to its limited application, and to that end, the improved linear equation and nonlinear fitting models, and gradient processing method were developed on the basis of the assumed behaviour of how a medium’s scattering coefficient changes with wavelength to provide information about the fractional concentration value of an absorber. The performance of these techniques evaluated via simulation showed that linear equation model has the fastest processing speed, nonlinear fitting method is robust to system noise and is able to provide an overall more accurate estimate of value with mean of errors of less than ±1%. The gradient processing method has intermediate performances with accuracy of its estimated value improved by about 30% with an increase in the spectral resolution from 1 nm to 0.5 nm. This work concludes that gradient processing method would be employed if accuracy of estimated value, noise robustness and computing time are of concern. However, nonlinear fitting method would be chosen in case high accuracy of the estimated value is required. Both of these methods can be suitably used as complementary techniques to clinical assessment of skin grafts and burnt skin. The simultaneous solution of linear equation model works well if all the measurement parameters are known. 2012-03-15 Thesis (University of Nottingham only) NonPeerReviewed application/pdf en arr https://eprints.nottingham.ac.uk/12464/1/Audrey_Huong_Thesis.pdf Huong, Audrey Kah Ching (2012) Spectroscopic analysis of scattering media via different quantification techniques. PhD thesis, University of Nottingham. Spectroscopy Blood oxygen saturation Light scattering Absorption Light attenuation
spellingShingle Spectroscopy
Blood oxygen saturation
Light scattering
Absorption
Light attenuation
Huong, Audrey Kah Ching
Spectroscopic analysis of scattering media via different quantification techniques
title Spectroscopic analysis of scattering media via different quantification techniques
title_full Spectroscopic analysis of scattering media via different quantification techniques
title_fullStr Spectroscopic analysis of scattering media via different quantification techniques
title_full_unstemmed Spectroscopic analysis of scattering media via different quantification techniques
title_short Spectroscopic analysis of scattering media via different quantification techniques
title_sort spectroscopic analysis of scattering media via different quantification techniques
topic Spectroscopy
Blood oxygen saturation
Light scattering
Absorption
Light attenuation
url https://eprints.nottingham.ac.uk/12464/