Transgenic nematodes as a model for Parkinson’s disease

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Transgenic nematodes as a model for Parkinson’s disease

Aggregation of the abundant neural protein α-synuclein contributes to cellular toxicity in Parkinson‘s disease. We have created transgenic nematodes carrying fusion constructs encoding human α-synuclein (S) tagged with YFP (V) and/or CFP (C) as a fluorescent marker. Using the unc-54 myosin promoter,...

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Bibliographic Details
Main Author:	Bodhicharla, Rakesh Kumar
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2012
Online Access:	https://eprints.nottingham.ac.uk/12108/

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