Stochastic epidemic models for emerging diseases incorporating household structure and contact tracing

In this thesis, three stochastic epidemic models for intervention for emerging diseases are considered. The models are variants of real-time, responsive intervention, based upon observing diagnosed cases and targeting intervention towards individuals they have infected or are likely to have infected...

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Main Author: Knock, Edward Stuart
Format: Thesis (University of Nottingham only)
Language:English
Published: 2011
Online Access:https://eprints.nottingham.ac.uk/12046/
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author Knock, Edward Stuart
author_facet Knock, Edward Stuart
author_sort Knock, Edward Stuart
building Nottingham Research Data Repository
collection Online Access
description In this thesis, three stochastic epidemic models for intervention for emerging diseases are considered. The models are variants of real-time, responsive intervention, based upon observing diagnosed cases and targeting intervention towards individuals they have infected or are likely to have infected, be they housemates or named contacts. These models are: (i) a local tracing model for a disease spreading amongst a community of households, wherein intervention (vaccination and/or isolation) is directed towards housemates of diagnosed individuals, (ii) a contact tracing model for a disease spreading amongst a homogeneously-mixing population, with isolation of traced contacts of a diagnosed individual, (iii) a local tracing and contact tracing model for a disease spreading amongst a community of households, with intervention directed towards housemates of both diagnosed and traced individuals. These are quantified by deriving threshold parameters that determine whether the disease will infect a few individuals or a sizeable proportion of the population, as well as probabilities for such events occurring.
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format Thesis (University of Nottingham only)
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institution University of Nottingham Malaysia Campus
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language English
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publishDate 2011
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spelling nottingham-120462025-02-28T11:17:11Z https://eprints.nottingham.ac.uk/12046/ Stochastic epidemic models for emerging diseases incorporating household structure and contact tracing Knock, Edward Stuart In this thesis, three stochastic epidemic models for intervention for emerging diseases are considered. The models are variants of real-time, responsive intervention, based upon observing diagnosed cases and targeting intervention towards individuals they have infected or are likely to have infected, be they housemates or named contacts. These models are: (i) a local tracing model for a disease spreading amongst a community of households, wherein intervention (vaccination and/or isolation) is directed towards housemates of diagnosed individuals, (ii) a contact tracing model for a disease spreading amongst a homogeneously-mixing population, with isolation of traced contacts of a diagnosed individual, (iii) a local tracing and contact tracing model for a disease spreading amongst a community of households, with intervention directed towards housemates of both diagnosed and traced individuals. These are quantified by deriving threshold parameters that determine whether the disease will infect a few individuals or a sizeable proportion of the population, as well as probabilities for such events occurring. 2011-07-13 Thesis (University of Nottingham only) NonPeerReviewed application/pdf en arr https://eprints.nottingham.ac.uk/12046/1/eknockfinishedthesis.pdf Knock, Edward Stuart (2011) Stochastic epidemic models for emerging diseases incorporating household structure and contact tracing. PhD thesis, University of Nottingham.
spellingShingle Knock, Edward Stuart
Stochastic epidemic models for emerging diseases incorporating household structure and contact tracing
title Stochastic epidemic models for emerging diseases incorporating household structure and contact tracing
title_full Stochastic epidemic models for emerging diseases incorporating household structure and contact tracing
title_fullStr Stochastic epidemic models for emerging diseases incorporating household structure and contact tracing
title_full_unstemmed Stochastic epidemic models for emerging diseases incorporating household structure and contact tracing
title_short Stochastic epidemic models for emerging diseases incorporating household structure and contact tracing
title_sort stochastic epidemic models for emerging diseases incorporating household structure and contact tracing
url https://eprints.nottingham.ac.uk/12046/