Characterisation of the physico-chemical and solid-state behaviour of drugs in HFA-134 and 227

Characterisation of the physico-chemical and solid-state behaviour of drugs in HFA-134 and 227

Most drugs have a considerably low solubility in the environmentally friendly hydrofluoroalkane propellants (HFAs) currently used in pressurized metered dose inhalers (pMDIs). As a consequence, instability can occur from crystal growth and Ostwald ripening of the system altering the therapeutic perf...

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Bibliographic Details
Main Author: Bouhroum, Abdennour
Format: Thesis (University of Nottingham only)
Language:English
Published: 2011
Online Access:https://eprints.nottingham.ac.uk/12004/

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