Investigations of the DEAD-box helicase eIF4A

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Investigations of the DEAD-box helicase eIF4A

Eukaryotic Initiation Factor (eIF) 4A is the most abundant initiation factor and the prototypical member of the DEAD-box family of helicases. Once recruited to the cap-binding complex, eIF4F, eIF4A unwinds inhibitory RNA secondary structure in the 5’ untranslated region (UTR) of mRNAs, promoting ef...

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Bibliographic Details
Main Author:	Phillips, Nicola Marie
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2011
Online Access:	https://eprints.nottingham.ac.uk/11991/

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