Synthesis of drug intermediates in carbon dioxide

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Synthesis of drug intermediates in carbon dioxide

The application of supercritical C0₂(scC0₂) as a solvent for the synthesis of fine and bulk chemicals has been well documented; however its application as a solvent for the synthesis of pharmaceuticals is yet to be exploited fully. To address this issue, two synthetically important reactions have be...

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Bibliographic Details
Main Author:	Clark, Peter David
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2007
Subjects:	supercritical carbon dioxide drug synthesis chemoselective N-debenzylation diastereoselective hydrogenation green chemistry
Online Access:	https://eprints.nottingham.ac.uk/11912/

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