An investigation into the effects of the epidermal growth factor receptor tyrosine kinase inhibitor "Gefitinib" on human breast cancer

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An investigation into the effects of the epidermal growth factor receptor tyrosine kinase inhibitor "Gefitinib" on human breast cancer

Background. In vitro studies have shown that ER+ acquired tamoxifen resistant MCF7 breast cancer cell lines can show elevated levels of EGFR expression with an increase in its subsequent signalling pathway(s) and that these are growth inhibited by gefitinib, an EGFR tyrosine kinase inhibitor. This t...

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Bibliographic Details
Main Author:	Gutteridge, Eleanor
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2010
Online Access:	https://eprints.nottingham.ac.uk/11576/

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