Determinants of vacuolating cytotoxin production and its impact on Helicobacter pylori pathogenesis

Determinants of vacuolating cytotoxin production and its impact on Helicobacter pylori pathogenesis

Introduction: The vacuolating cytotoxin is an important H. pylori virulence factor and is naturally polymorphic, one of the most diverse regions being the signal region (type s1 or s2). Signal type determines vacuolating activity: type s1 strains are vacuolating and are associated with peptic ulcers...

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Bibliographic Details
Main Author: Masters, Charlotte Grace
Format: Thesis (University of Nottingham only)
Language:English
Published: 2010
Online Access:https://eprints.nottingham.ac.uk/11139/

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