Development of clickable approaches to build functional polymeric nanoparticles
Smart functional nanoparticles have attracted considerable interest over the last few years due to their unique properties and behaviours, which could be used in a wide range of applications such as diagnostics and drug delivery. Nanoparticles based on polyacrylamide matrices were constructed using...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2010
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| Online Access: | https://eprints.nottingham.ac.uk/11107/ |
| _version_ | 1848791195300397056 |
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| author | Makawitage, Daminda Ayal Perera |
| author_facet | Makawitage, Daminda Ayal Perera |
| author_sort | Makawitage, Daminda Ayal Perera |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Smart functional nanoparticles have attracted considerable interest over the last few years due to their unique properties and behaviours, which could be used in a wide range of applications such as diagnostics and drug delivery.
Nanoparticles based on polyacrylamide matrices were constructed using free radical polymerisation methodology. Moreover, newly designed azido, alkyne and maleimido functional groups bearing nanoparticles were synthesised, and their unique chemical properties were comprehensively evaluated.
The contribution of monomer composition to the size distribution of particles was studied. The availability of the newly introduced functional groups was confirmed by clicking fluorogenic substrates followed by spectroscopic studies. |
| first_indexed | 2025-11-14T18:24:39Z |
| format | Thesis (University of Nottingham only) |
| id | nottingham-11107 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T18:24:39Z |
| publishDate | 2010 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-111072025-02-28T11:11:17Z https://eprints.nottingham.ac.uk/11107/ Development of clickable approaches to build functional polymeric nanoparticles Makawitage, Daminda Ayal Perera Smart functional nanoparticles have attracted considerable interest over the last few years due to their unique properties and behaviours, which could be used in a wide range of applications such as diagnostics and drug delivery. Nanoparticles based on polyacrylamide matrices were constructed using free radical polymerisation methodology. Moreover, newly designed azido, alkyne and maleimido functional groups bearing nanoparticles were synthesised, and their unique chemical properties were comprehensively evaluated. The contribution of monomer composition to the size distribution of particles was studied. The availability of the newly introduced functional groups was confirmed by clicking fluorogenic substrates followed by spectroscopic studies. 2010-07-20 Thesis (University of Nottingham only) NonPeerReviewed application/pdf en arr https://eprints.nottingham.ac.uk/11107/1/Thesis.pdf Makawitage, Daminda Ayal Perera (2010) Development of clickable approaches to build functional polymeric nanoparticles. MRes thesis, University of Nottingham. nanoparticles nanosensors polyacrylamide matrices monomers |
| spellingShingle | nanoparticles nanosensors polyacrylamide matrices monomers Makawitage, Daminda Ayal Perera Development of clickable approaches to build functional polymeric nanoparticles |
| title | Development of clickable approaches to build functional polymeric nanoparticles |
| title_full | Development of clickable approaches to build functional polymeric nanoparticles |
| title_fullStr | Development of clickable approaches to build functional polymeric nanoparticles |
| title_full_unstemmed | Development of clickable approaches to build functional polymeric nanoparticles |
| title_short | Development of clickable approaches to build functional polymeric nanoparticles |
| title_sort | development of clickable approaches to build functional polymeric nanoparticles |
| topic | nanoparticles nanosensors polyacrylamide matrices monomers |
| url | https://eprints.nottingham.ac.uk/11107/ |