Towards understanding latrophilin signalling in C.elegans

QR Code

Towards understanding latrophilin signalling in C.elegans

Latrophilin (LAT-1) is a G -protein-coupled receptor (GPCR), and mediates Black widow spider venom toxicity (Mee et al., 2004). A deletion in the lat-1(ok1465) gene (allele ok1465) in C. elegans causes 97% of worms to die during embryogenesis or early larval stages (Adenle, 2008). Thus latrophilin h...

Full description

Bibliographic Details
Main Author:	Al-Harbi, Hamad
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2010
Subjects:	latrophilin latrophilin signalling cell receptors secretin C. elegans
Online Access:	https://eprints.nottingham.ac.uk/11032/

Similar Items

Toxicology studies in Caenorhabditis elegans
by: Budd, Chloe Denisha
Published: (2008)

Functional phosphatome requirement for protein homeostasis, networked mitochondria, and sarcomere structure in C. elegans muscle
by: Lehmann, Susann, et al.
Published: (2017)

Effects of khat ethanol extract, cathinone and cathine on cytochrome P450 activities in vitro, molecular docking CYP-cathinone and CYP-cathine interactions and in vivo effects on Caenorhabditis elegans
by: Lim, Sharoen Yu Ming
Published: (2024)

Genetic analysis of latrophilin in the toxicity of combined latrotoxins for C. elegans
by: Adenle, Ademola A.
Published: (2010)

Use of transgenic GFP reporter strains of the nematode Caenorhabditis elegans to investigate the patterns of stress responses induced by pesticides and by organic extracts from agricultural soils
by: Anbalagan, Charumathi, et al.
Published: (2013)

Glutathione reductase gsr-1 is an essential gene required for Caenorhabditis elegans early embryonic development
by: Mora-Lorca, José Antonio, et al.
Published: (2016)

Calcium signal propagation in astrocytes
by: Burrows, Sean
Published: (2021)

Molecular Genetic Analysis of the alpha-latrotoxin Receptor Latrophilin in the Nematode Caenorhabditis elegans.
by: Mee, Christopher
Published: (2002)

Effects of α-synuclein overexpression in transgenic Caenorhabditis elegans strains
by: Bodhicharla, Rakesh, et al.
Published: (2012)

Investigating the molecular basis of biased signalling at cannabinoid receptors
by: Dennis, Morgan Jane
Published: (2023)

Modulation of mu-opioid receptor dynamics at the plasma membrane and its implications for signalling and trafficking
by: Underwood, Owen George
Published: (2024)

Crystal structure of signal regulatory protein gamma (SIRPγ) in complex with an antibody Fab fragment
by: Nettleship, Joanne E., et al.
Published: (2013)

Exploring the effects of medicinal fungi on isolated bladder strips (ex vivo) and Caenorhabditis elegans (in vivo): focus on the caterpillar fungus, Ophiocordyceps sinensis
by: Pang, Li Yin
Published: (2024)

DEF6, a novel substrate for the tec kinase ITK, contains a glutamine-rich aggregation-prone region and forms cytoplasmic granules that co-localize with P-bodies
by: Hey, Fiona, et al.

Multiscale analysis of pattern formation via intercellular signalling
by: O'Dea, Reuben D., et al.
Published: (2011)

Preparation, characterisation and applications : Boron nitride nanotubes (BNNTs), BNNTs-graphene hybrid and their polymer nanocomposites
by: Kakarla, Akesh Babu
Published: (2018)

Novel complementation biosensors to investigate G protein-coupled receptor kinetics and signalling bias
by: Dijon, Nicola C
Published: (2022)

Remote automated multi-generational growth and observation of an animal in low Earth orbit
by: Oczypok, Elizabeth A., et al.
Published: (2012)

Fundamental properties of Ca²⁺ signals
by: Thurley, Kevin, et al.
Published: (2011)

Allosteric interactions at adenosine A1 and A3 receptors: new insights into the role of small molecules and receptor dimerization
by: Hill, Stephen J., et al.
Published: (2014)

Transgenic nematodes as biosensors for metal stress in soil pore water samples
by: Anbalagan, Charumathi, et al.
Published: (2012)

Non-classical mechanisms of steroid sensing in the ovary: lessons from the bovine oxytocin model
by: Ivell, Richard, et al.
Published: (2014)

The role of NagC in Yersinia pestis and Yersinia pseudotuberculosis biofilm development and insect transmission
by: Elton, Linzy
Published: (2019)

The reproductive biology and conservation of two rare Banksia species.
by: Barrett, Gregory J.
Published: (1985)

The effects of Pseudomonas aeruginosa quorum sensing signalling molecules on human T cell function
by: Huynh, Tina
Published: (2008)

Human dendritic cell sequestration onto the Necator americanus larval sheath during ex-sheathing: a possible mechanism for immune privilege
by: Hassan, A., et al.
Published: (2018)

The mannose receptor negatively modulates the Toll-like receptor 4–aryl hydrocarbon receptor–indoleamine 2,3-dioxygenase axis in dendritic cells affecting T helper cell polarization
by: Salazar, Fabián, et al.
Published: (2016)

Classification of Electroencephalogram Signals for Human Motor Actions
by: Paoliello, Daniel, et al.
Published: (2010)

Molecular pharmacology of VEGF-A isoforms: binding and signalling at VEGFR2
by: Peach, Chloe, et al.
Published: (2018)

Microstructure and properties of C/C–ZrC composites prepared by hydrothermal deposition combined with carbothermal reduction
by: Li, Cuiyan, et al.
Published: (2018)

The identification of STAT2 as a pervasive negative regulator of STAT1 activity and cytokine signalling
by: Ho, Johnathan
Published: (2018)

Application of BRET to monitor ligand binding to GPCRs
by: Stoddart, Leigh A., et al.
Published: (2015)

Corticosterone and dopamine D2/D3 receptors mediate the motivation for voluntary wheel running in C57BL/6J mice
by: Ebada, Mohamed Elsaed Elsayed, et al.
Published: (2016)

Recognition of membrane sterols by polyene antifungals amphotericin B and natamycin, a 13C MAS NMR Study
by: Ciesielski, Filip, et al.
Published: (2016)

The role of indoleamine 2,3-dioxygenase in modulating allergic responses
by: Salazar, F.
Published: (2016)

Investigating Molecular Interactions of Thyroid Hormone and Androgen Receptors
by: Zhao, Yi
Published: (2023)

HfB2-SiC-MoSi2 oxidation resistance coating fabricated through in-situ synthesis for SiC coated C/C composites
by: Wang, Peipei, et al.
Published: (2017)

Measurements of Doppler and delay spreading of communication signals in medium depth and shallow underwater acoustic channels
by: Caley, Michael, et al.
Published: (2012)

SCIB2, an antibody DNA vaccine encoding NY-ESO-1 epitopes, induces potent antitumor immunity which is further enhanced by checkpoint blockade
by: Xue, Wei, et al.
Published: (2016)

The amino-terminal domain of the androgen receptor co-opts extracellular signal-regulated kinase (ERK) docking sites in ELK1 protein to induce sustained gene activation that supports prostate cancer cell growth
by: Rosati, Rayna, et al.
Published: (2016)