The role of the pyruvate dehydrogenase complex in the regulation of human skeletal muscle fuel metabolism
The pyruvate dehydrogenase complex (PDC) is the rate limiting step in the entry of glucose derived pyruvate into the tricarboxylic acid (TCA) cycle. As such it plays an important role in the control of the use of carbohydrate as the source of oxidative energy for skeletal muscle contraction. The...
| Main Author: | Laithwaite, David |
|---|---|
| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2009
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/10992/ |
Similar Items
The heterogeneity of the functional, metabolic, and molecular responses of skeletal muscle and clinical adaptations to exercise training in pre-clinical and human models
by: Farrash, Wesam
Published: (2020)
by: Farrash, Wesam
Published: (2020)
Investigation of molecular mechanisms regulating palmitate-induced metabolic inflexibility in a cell-based skeletal muscle model: physiological and pharmacological interventions.
by: Chien, Hung-Che
Published: (2020)
by: Chien, Hung-Che
Published: (2020)
Muscle carnitine availability plays a central role in regulating fuel metabolism in the rodent
by: Porter, Craig, et al.
Published: (2017)
by: Porter, Craig, et al.
Published: (2017)
Investigation of muscle mass and metabolic regulation in human volunteers: the impact of resistance exercise, pharmacological intervention and obesity
by: Taylor, Tariq Yaqub
Published: (2020)
by: Taylor, Tariq Yaqub
Published: (2020)
The effect of vitamin D on the development and function of skeletal muscle
by: Alliband, Kathryn
Published: (2024)
by: Alliband, Kathryn
Published: (2024)
Human skeletal muscle disuse atrophy: effects on muscle protein synthesis, breakdown and insulin resistance- a qualitative review
by: Rudrappa, Supreeth S., et al.
Published: (2016)
by: Rudrappa, Supreeth S., et al.
Published: (2016)
Impact of the calcium form of β-hydroxy-β-methylbutyrate upon human skeletal muscle protein metabolism
by: Wilkinson, Daniel J., et al.
Published: (2017)
by: Wilkinson, Daniel J., et al.
Published: (2017)
Pain behaviour, locomotor activity, inflammation and muscle metabolic dysregulation in pre-clinical animal models of OA and RA and the impact of PPARɣ agonism intervention
by: Casanova, Nuria
Published: (2019)
by: Casanova, Nuria
Published: (2019)
Early structural remodeling and deuterium oxide-derived protein metabolic responses to eccentric and concentric loading in human skeletal muscle
by: Franchi, Martino V., et al.
Published: (2015)
by: Franchi, Martino V., et al.
Published: (2015)
Very low-energy diets in overweight-to-obese, middle-aged men with type two diabetes mellitus or prediabetes: the musculoskeletal and metabolic effects of adjunct high-intensity interval training
by: Ardavani, Arash
Published: (2024)
by: Ardavani, Arash
Published: (2024)
The role of the vitamin D receptor in skeletal muscle protein metabolism
by: Bass, Joseph
Published: (2017)
by: Bass, Joseph
Published: (2017)
Effect of Diet, Insulin and Exercise on the Regulation of Carbohydrate Metabolism in Health and Type 1 Diabetes
by: Chokkalingam, Kamalakkannan
Published: (2007)
by: Chokkalingam, Kamalakkannan
Published: (2007)
Development and application of minimally invasive stable isotope tracers’ measures of muscle mass and muscle protein synthesis/breakdown: insights into ageing skeletal muscle
by: Cegielski, Jessica
Published: (2020)
by: Cegielski, Jessica
Published: (2020)
Exploring the effects of ageing, cancer, and exercise on skeletal muscle mitochondrial function
by: Smart, Thomas
Published: (2024)
by: Smart, Thomas
Published: (2024)
The impact of immobilisation and inflammation on the regulation of muscle mass and insulin resistance: different routes to similar end points
by: Crossland, Hannah, et al.
Published: (2018)
by: Crossland, Hannah, et al.
Published: (2018)
Pharmacological enhancement of leg and muscle microvascular blood flow does not augment anabolic responses in skeletal muscle of young men under fed conditions
by: Phillips, Bethan E., et al.
Published: (2014)
by: Phillips, Bethan E., et al.
Published: (2014)
Metabolic phenotyping in cells and tissues using pyruvate metabolism and nuclear magnetic resonance spectroscopy
by: Silickas, Marius
Published: (2021)
by: Silickas, Marius
Published: (2021)
A novel ketone diet enhances physical and cognitive performance
by: Murray, Andrew J., et al.
Published: (2016)
by: Murray, Andrew J., et al.
Published: (2016)
Metabolic and functional characterisation of adult skeletal muscle in down syndrome mouse model (Ts1CJe) for insights into hypotonia in human condition
by: Lim, Chai Ling
Published: (2017)
by: Lim, Chai Ling
Published: (2017)
Amino acid modulation of gut hormone release and defining roles of GLP-1 and insulin in muscle microcirculation and metabolism in older age
by: Abdulla, Haitham M.A.
Published: (2018)
by: Abdulla, Haitham M.A.
Published: (2018)
The roles of muscle contraction and pharmaceuticals on
restoring glucose uptake in a mouse skeletal muscle
model of immobilization
by: Kirkpatrick, Euan
Published: (2024)
by: Kirkpatrick, Euan
Published: (2024)
The metabolic and molecular mechanisms of hyperammonaemia and hyperethanolaemia induced protein catabolism in skeletal muscle cells
by: Crossland, Hannah, et al.
Published: (2018)
by: Crossland, Hannah, et al.
Published: (2018)
Analysis of molecular links between epigenetic regulations and energy metabolism
by: Miezaniec, Agata
Published: (2020)
by: Miezaniec, Agata
Published: (2020)
Mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M) and serine biosynthetic pathway genes are co-ordinately increased during anabolic agent-induced skeletal muscle growth
by: Brown, D.M., et al.
Published: (2016)
by: Brown, D.M., et al.
Published: (2016)
Impact of isoenergetic intake of irregular meal patterns on energy expenditure metabolism and appetite regulation
by: Alhussain, Maha
Published: (2016)
by: Alhussain, Maha
Published: (2016)
The impact of leucine-enriched whey protein on skeletal muscle anabolism
by: Ely, Isabel
Published: (2024)
by: Ely, Isabel
Published: (2024)
Skeletal muscle remodeling in response to eccentric vs. concentric loading: morphological, molecular, and metabolic adaptations
by: Franchi, Martino V., et al.
Published: (2017)
by: Franchi, Martino V., et al.
Published: (2017)
Supplementing essential amino acids with the nitric oxide precursor, l-arginine, enhances skeletal muscle perfusion without impacting anabolism in older men
by: Mitchell, W. Kyle, et al.
Published: (2017)
by: Mitchell, W. Kyle, et al.
Published: (2017)
Increasing cardiac pyruvate dehydrogenase flux during chronic hypoxia improves acute hypoxic tolerance
by: Handzlik, Michal, et al.
Published: (2018)
by: Handzlik, Michal, et al.
Published: (2018)
Modulation of muscle protein metabolism through amino acid supplementation and exercise in older women
by: Bukhari, Syed Shabbar Ijaz
Published: (2020)
by: Bukhari, Syed Shabbar Ijaz
Published: (2020)
A novel puromycin decorporation method to quantify skeletal muscle protein breakdown: a proof-of-concept study
by: Crossland, Hannah, et al.
Published: (2017)
by: Crossland, Hannah, et al.
Published: (2017)
Impact of polyphenols on lipid accumulation within skeletal muscle cells
by: Alhodieb, Fahad
Published: (2020)
by: Alhodieb, Fahad
Published: (2020)
Endocrine and immune responses to resistance training in prostate cancer patients
by: Galvao, D, et al.
Published: (2008)
by: Galvao, D, et al.
Published: (2008)
The role of skeletal muscle in the initiation and progression of knee osteoarthritis
by: Tonge, Daniel Paul
Published: (2010)
by: Tonge, Daniel Paul
Published: (2010)
Effects of leucine-enriched essential amino acid and whey protein bolus dosing upon skeletal muscle protein synthesis at rest and after exercise in older women
by: Wilkinson, Daniel J., et al.
Published: (2017)
by: Wilkinson, Daniel J., et al.
Published: (2017)
Effects of replacing diet beverages with water on weight loss, carbohydrate and lipid metabolism during a hypoenergetic diet
by: Madjd Jabari, Seyedeh Ameneh
Published: (2017)
by: Madjd Jabari, Seyedeh Ameneh
Published: (2017)
Differential nitric oxide levels in the blood and skeletal muscle of Type 2 diabetic subjects may be consequence of adiposity: a preliminary study.
by: Krause, M., et al.
Published: (2012)
by: Krause, M., et al.
Published: (2012)
Photoperiodic regulation of FGF21 production in the Siberian hamster
by: Samms, Ricardo J., et al.
Published: (2014)
by: Samms, Ricardo J., et al.
Published: (2014)
Development and application of novel stable isotopic approaches to study human skeletal muscle in response to exercise and ageing
by: Brook, Matthew
Published: (2017)
by: Brook, Matthew
Published: (2017)
Reduced adiposity attenuates FGF21 mediated metabolic improvements in the Siberian hamster
by: Lewis, Jo E., et al.
Published: (2017)
by: Lewis, Jo E., et al.
Published: (2017)
Similar Items
-
The heterogeneity of the functional, metabolic, and molecular responses of skeletal muscle and clinical adaptations to exercise training in pre-clinical and human models
by: Farrash, Wesam
Published: (2020) -
Investigation of molecular mechanisms regulating palmitate-induced metabolic inflexibility in a cell-based skeletal muscle model: physiological and pharmacological interventions.
by: Chien, Hung-Che
Published: (2020) -
Muscle carnitine availability plays a central role in regulating fuel metabolism in the rodent
by: Porter, Craig, et al.
Published: (2017) -
Investigation of muscle mass and metabolic regulation in human volunteers: the impact of resistance exercise, pharmacological intervention and obesity
by: Taylor, Tariq Yaqub
Published: (2020) -
The effect of vitamin D on the development and function of skeletal muscle
by: Alliband, Kathryn
Published: (2024)