Stem cells for enhancing recovery after stroke: a review

The potential application for stem cell therapy is vast, and development for use in ischaemic stroke is still in its infancy. Access to stem cells for research is contentious; however, stem cells are obtainable from both animal and human. Despite a limited understanding of their mechanisms of actio...

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Main Authors: England, Timothy J., Martin, Paul, Bath, Philip M.W.
Format: Article
Published: 2009
Online Access:https://eprints.nottingham.ac.uk/1082/
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author England, Timothy J.
Martin, Paul
Bath, Philip M.W.
author_facet England, Timothy J.
Martin, Paul
Bath, Philip M.W.
author_sort England, Timothy J.
building Nottingham Research Data Repository
collection Online Access
description The potential application for stem cell therapy is vast, and development for use in ischaemic stroke is still in its infancy. Access to stem cells for research is contentious; however, stem cells are obtainable from both animal and human. Despite a limited understanding of their mechanisms of action, clinical trials assessing stem cells in human stroke have been performed. Trials are also underway evaluating haematopoietic precursors mobilised with granulocyte-colony stimulating factor, an approach offering an autologous means of administrating stem cells for therapeutic purposes. This review summarises current knowledge in regard to stem cells and their potential for helping improve recovery after stroke.
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spelling nottingham-10822020-05-04T20:26:20Z https://eprints.nottingham.ac.uk/1082/ Stem cells for enhancing recovery after stroke: a review England, Timothy J. Martin, Paul Bath, Philip M.W. The potential application for stem cell therapy is vast, and development for use in ischaemic stroke is still in its infancy. Access to stem cells for research is contentious; however, stem cells are obtainable from both animal and human. Despite a limited understanding of their mechanisms of action, clinical trials assessing stem cells in human stroke have been performed. Trials are also underway evaluating haematopoietic precursors mobilised with granulocyte-colony stimulating factor, an approach offering an autologous means of administrating stem cells for therapeutic purposes. This review summarises current knowledge in regard to stem cells and their potential for helping improve recovery after stroke. 2009-04 Article PeerReviewed England, Timothy J., Martin, Paul and Bath, Philip M.W. (2009) Stem cells for enhancing recovery after stroke: a review. International Journal of Stroke, 4 (2). pp. 101-110. ISSN 1747-4949 http://www.wiley.com/bw/journal.asp?ref=1747-4930
spellingShingle England, Timothy J.
Martin, Paul
Bath, Philip M.W.
Stem cells for enhancing recovery after stroke: a review
title Stem cells for enhancing recovery after stroke: a review
title_full Stem cells for enhancing recovery after stroke: a review
title_fullStr Stem cells for enhancing recovery after stroke: a review
title_full_unstemmed Stem cells for enhancing recovery after stroke: a review
title_short Stem cells for enhancing recovery after stroke: a review
title_sort stem cells for enhancing recovery after stroke: a review
url https://eprints.nottingham.ac.uk/1082/
https://eprints.nottingham.ac.uk/1082/