Interplay between hypoxia and gastrin in gastrointestinal cancer

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Interplay between hypoxia and gastrin in gastrointestinal cancer

Tumour hypoxia has been linked to increased resistance to both radiotherapy and chemotherapy, especially in solid metastatic GI tumours. Under hypoxic conditions, genes that promote tumour growth and survival are up-regulated, via the transcription factor hypoxia-inducible factor-1 (HIF-1). The dige...

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Bibliographic Details
Main Author:	Royal, E.L.
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2009
Subjects:	Gastrointestinal cancer Gastrin Hypoxia Cancer cells
Online Access:	https://eprints.nottingham.ac.uk/10805/

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