Integrative biological studies of anti-tumour agents

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Integrative biological studies of anti-tumour agents

3, 11-difluoro-6, 8, 13-trimethyl-8H- quino [4, 3, 2-kl] acridinium methosulfate (RHPS4) is a member of a series of pentacyclic acridines developed at the University of Nottingham, which bind to, and stabilise the structure of G-quadruplex DNA and inhibit the action of telomerase at sub-micromolar c...

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Bibliographic Details
Main Author:	Johnson, L.A.
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2009
Online Access:	https://eprints.nottingham.ac.uk/10800/

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