Defining and manipulating the epigenetic stability of human embryonic stem cells

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Defining and manipulating the epigenetic stability of human embryonic stem cells

This thesis aimed to define and manipulate epigenetic stability of human embryonic stem cells (hESCs). The allele-specific expression of 22 imprinted genes was examined in 22 hESC lines by distinguishing parental single nucleotide polymorphisms in genomic DNA and cDNA. Half of the genes examined (PE...

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Bibliographic Details
Main Author:	Kim, Kee-Pyo
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2009
Subjects:	Epigenesis Embryonic stem cells Genetic manipulation
Online Access:	https://eprints.nottingham.ac.uk/10699/

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