Can we improve the statistical analysis of stroke trials?
Statistical reanalysis of functional outcomes in stroke trials

QR Code

Can we improve the statistical analysis of stroke trials? Statistical reanalysis of functional outcomes in stroke trials

Background and Purpose—Most large acute stroke trials have been neutral. Functional outcome is usually analyzed using a yes or no answer, eg, death or dependency versus independence. We assessed which statistical approaches are most efficient in analyzing outcomes from stroke trials. Methods—Indivi...

Full description

Bibliographic Details
Main Author:	Optimising Analysis of Stroke Trials Collaboration, OAST
Format:	Article
Published:	American Heart Association Inc 2007
Online Access:	https://eprints.nottingham.ac.uk/1059/

Similar Items

Calculation of sample size for stroke trials assessing functional outcome: comparison of binary and ordinal approaches
by: The Optimising Analysis of Stroke Trials Collaboration, OAST
Published: (2008)

Can we improve the statistical analysis of stroke trials? Statistical re-analysis of functional outcomes in stroke trials
by: Bath, Philip
Published: (2007)

Can we improve the statistical analysis of stroke trials? Statistical re-analysis of functional outcomes in stroke trials
by: Bath, Philip M.W.
Published: (2007)

Statistical reanalysis of vascular event outcomes in primary and secondary vascular prevention trials
by: Woodhouse, Lisa Jane
Published: (2022)

Adjudicating outcomes in stroke trials
by: Godolphin, Peter J.
Published: (2019)

Statistical analysis plan for the ‘Efficacy of Nitric Oxide in Stroke’ (ENOS) trial
by: Bath, Philip M.W., et al.
Published: (2014)

Ordinal reanalysis of the SHEP Trial
by: Bath, Philip M.W., et al.
Published: (2008)

Statistical analysis plan for the ‘Triple Antiplatelets for Reducing Dependency after Ischaemic Stroke’ (TARDIS) trial
by: Bath, Philip M.W., et al.
Published: (2015)

Statistical analysis plan for the ‘Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2)’
by: Scutt, Polly, et al.
Published: (2018)

Optimising the analysis of stroke trials
by: Gray, Laura Jayne
Published: (2008)

The Virtual International Stroke Trials Archive
by: Myzoon, Ali, et al.
Published: (2007)

Stroke outcome in clinical trial patients deriving from different countries
by: Ali, Myzoon, et al.
Published: (2008)

Stroke severity, early recovery and outcome are each related with clinical classification of stroke: data from the 'Tinzaparin in Acute Ischaemic Stroke Trial (TAIST)
by: Sprigg, Nikola, et al.
Published: (2007)

Stroke severity, early recovery and outcome are each related with clinical classification of stroke: Data from the 'Tinzaparin in Acute Ischaemic Stroke Trial (TAIST)
by: Sprigg, Nikola, et al.
Published: (2007)

Significant variation in mortality and functional outcome after acute ischaemic stroke between western countries: data from the 'Tinzaparin in Acute Ischaemic Stroke Trial' (TAIST)
by: Gray, Laura J., et al.
Published: (2006)

Describing return to work after stroke : a feasibility trial of 12-month outcomes
by: Radford, Kathryn, et al.
Published: (2020)

Serum amyloid protein is associated with outcome following acute ischaemic stroke: data from the REmote ischaemic Conditioning After Stroke Trial (RECAST)
by: Appleton, Jason P., et al.
Published: (2018)

The effectiveness of structured intervention programme for stroke (sips) in improving stroke awareness and reducing stroke risk among adult population in Malaysia: a cluster randomised controlled trial
by: Said, Mohamad Zarudin Mat
Published: (2022)

Relationship between race and outcome in Asian, Black and Caucasian patients with spontaneous intracerebral haemorrhage: data from the Virtual International Stroke Trials Archive (VISTA) and Efficacy of Nitric Oxide in Stroke trial (ENOS)
by: Krishnan, Kailash, et al.
Published: (2018)

Statistical analysis plan (SAP) for the Very Early Rehabilitation in Speech (VERSE) after stroke trial: an international 3-arm clinical trial to determine the effectiveness of early, intensive, prescribed, direct aphasia therapy
by: Godecke, E., et al.
Published: (2018)

Remote Ischaemic Conditioning after Stroke Trial (RECAST): a pilot randomised placebo controlled phase II trial in acute ischaemic stroke (ISRCTN 86672015)
by: England, Timothy J., et al.
Published: (2017)

Sex differences in quality of life in stroke survivors. Data from the Tinzaparin in Acute Ischaemic Stroke Trial (TAIST)
by: Gray, Laura J., et al.
Published: (2007)

What is a return to work after stroke?: 12 month work outcomes in a feasibility trial
by: Sinclair, Emma, et al.
Published: (2014)

Lipid-lowering pretreatment and outcome following intravenous thrombolysis for acute ischaemic stroke: a post hoc analysis of the enhanced control of hypertension and thrombolysis stroke study trial
by: Minhas, Jatinder S., et al.
Published: (2018)

Consent procedures and relationship with outcome in the Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2)
by: Scutt, Polly, et al.
Published: (2018)

The DARS (Dopamine Augmented Rehabilitation in Stroke) trial: protocol for a randomised controlled trial of Co-careldopa treatment in addition to routine NHS occupational and physical therapy after stroke
by: Bhakta, BB, et al.
Published: (2014)

The DRESS trial: a feasibility randomized controlled trial of a neuropsychological approach to dressing therapy for stroke inpatients
by: Walker, Marion F., et al.
Published: (2012)

Family-led rehabilitation after stroke in India: the ATTEND trial, study protocol for a randomized controlled trial
by: Alim, Mohammed, et al.
Published: (2016)

Behavioral outcome measures to improve experimental stroke research
by: Balkaya, Mustafa G., et al.
Published: (2017)

The effect of transdermal glyceryl trinitrate in acute stroke patients with carotid stenosis: data from the Efficacy of Nitric Oxide in Stroke trial
by: Appleton, J.P., et al.
Published: (2018)

The effect of transdermal glyceryl trinitrate on imaging characteristics in acute ischaemic stroke: data from the Efficacy of Nitric Oxide in Stroke trial
by: Appleton, Jason P.
Published: (2018)

Statistical analysis plan for the EuroHYP-1 trial: European multicentre, randomised, phase III clinical trial of the therapeutic hypothermia plus best medical treatment versus best medical treatment alone for acute ischaemic stroke
by: Winkel, Per, et al.
Published: (2017)

The aspirin in reducing events in the elderly trial: Statistical analysis plan
by: Wolfe, R., et al.
Published: (2018)

A randomised controlled trial of occupational therapy for stroke patients not admitted to hospital
by: Walker, Marion Fraser
Published: (1999)

Family-led rehabilitation after stroke in India: a randomised controlled trial
by: Lindley, Richard, et al.
Published: (2017)

A randomized controlled trial of very early rehabilitation in speech after stroke
by: Godecke, E., et al.
Published: (2016)

PRECIOUS: PREvention of Complications to Improve OUtcome in elderly patients with acute Stroke: rationale and design of a randomised, open, phase III, clinical trial with blinded outcome assessment
by: Reinink, Hendrik, et al.
Published: (2018)

Exploring different models of stroke unit care and outcome : the Stroke Rehabilitation Outcome (SRO) study
by: Dennis, Diane
Published: (2013)

Intensive versus guideline blood pressure and lipid lowering in patients with previous stroke: main results from the pilot ‘Prevention of decline in cognition after stroke trial’ (PODCAST) randomised controlled trial
by: Bath, Philip M.W., et al.
Published: (2017)

Granulocyte colony stimulating factor and physiotherapy after stroke: results of a feasibility randomised controlled trial: stem cell trial of recovery enhancement after Stroke-3 (STEMS-3 ISRCTN16714730)
by: Sprigg, Nikola, et al.
Published: (2016)